Dmps/Dl-2, 3-Dimercapto-1-Propanesulfonic Acid

Sodium 2, 3-dimercaptopropanesulfonate monohydrate is a white crystalline powder soluble in water and alcohol. It has a strong foul odor and pungent odor. It can form coordination compounds containing sulfur divalent.

Intermediate for sodium dimecaptosuccinate(DMS), an antidote for heavy metal.Sodium 2,3-dimercaptopropanesulfonate monohydrate has been used in a study to assess its use as an antidote.

It is a broad-spectrum antidote of heavy metals, and is also used in the therapy of hepatolenticular degeneration, HLD (also known as Wilson's disease). Its effect on hydrargyrism is better than that of dimercaptopropanol, but it has lower toxicity. It is used as antidote of toxicosis from mercury, arsenic, chromium, bismuth, copper, antimony, etc. It is also effective on hepatolenticular degeneration, HLD (Wilson's disease) with long-term use.

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It is often used as a metal chelating agent and has good metal ion integration ability. Its chelation is mainly achieved through the formation of coordination bonds between the sulfhydryl group in dimercaptopropyl sulfonic acid and metal ions. Sulfhydryl group is a kind of functional group containing sulfur atoms, which has strong sulfur affinity and can form stable integrated complexes with metal ions.
DL-2,3-Dimercapto-1-propanesulfonic acid sodium salt monohydrate has been widely used in medical field. It can be used to treat moderate and severe lead poisoning, especially for children with lead poisoning. Sodium dimethylpropyl sulfonate promotes its excretion in the body by forming a stable complex with lead ion, thus playing a detoxification role. In addition, sodium dimercaptopropyl sulfonate can also be used to treat other heavy metal poisoning, such as bismuth, etc., has a certain detoxification effect.

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