Lidocaine HCl

Lidocaine hydrochloride is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of Lidocaine hydrochloride. Approximately 90% of Lidocaine hydrochloride administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.

1. Lidocaine, xylocaine, or lignocaine is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or as a local anesthetic for minor surgery.
 2.It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic healthcare system.
 3. Lidocaine is the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias if amiodarone is not available or contraindicated.
 4. Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.

Ons het baie fabrieke van hoë gehalte met diep samewerking, wat u produkte van hoë gehalte en mededingende pryse kan voorsien. En ons kan ook afslag gee vir grootmaat aankope. En ons werk saam met baie professionele vragversending maatskappye, kan produkte veilig en glad aan jou hande lewer. Afleweringstyd is ongeveer 3-20 dae na bevestiging van betaling.

1. Is jy 'n fabriek of 'n handelsmaatskappy?
Ons is 'n maatskappy wat industrie en handel integreer, wat eenstopdiens lewer. OEM kan aanvaar word.

2. Verskaf u monsters? Is dit gratis of ekstra?
Gratis monsters. Die monster se vragfooi moet aan jou kant betaal word.

3. Het u enige sertifikate wat verband hou met gehaltebeheer?
ISO 9001:2008-sertifisering om kwaliteit te verseker.

4. Wat moet ek verskaf om 'n kwotasie te kry?
Stel ons asseblief in kennis van die produktipe wat u benodig, bestelhoeveelheid, adres en spesifieke vereistes. Die kwotasie sal betyds vir u verwysing gemaak word.

5. Watter soort betaalmetode verkies jy? Watter soort terme word aanvaar?
Aanvaarde afleweringsbepalings: FOB, CFR, CIF, EXW;
Accepted Payment Currency:USD;EUR
Aanvaarde tipe betaling: T/T, Western Union; Paypal, Handelsversekering.
Gesproke taal: Engels.