4-bromo-3-fluorotoluene is an organic compound. The following is an introduction to its properties, manufacturing and safety information:
Nature:
4-bromo-3-fluorotoluene is a colorless liquid with a benzene ring structure and bromine and fluorine substituents. It has a pungent smell at room temperature. It is insoluble in cold water, but can be dissolved in organic solvents.
Preparation:
4-bromo-3-fluorotoluene is prepared by reacting hydrogen fluoride (HF) and hydrogen bromide (HBr) with appropriate tolyl compounds in a reaction system. This reaction needs to be carried out at the right temperature and pressure and with an acidic catalyst.
Safety information:
4-bromo-3-fluorotoluene is a toxic compound and should be avoided in direct contact with skin, eyes and respiratory tract. Wear appropriate protective equipment such as gloves, goggles and a protective face shield when using. When handling this compound, correct laboratory safety procedures should be followed and handled in a well-ventilated environment. Store in a dry, cool and well-ventilated place, away from fire sources and open flames. Any operation using this compound should be carried out under appropriate equipment and conditions and by personnel who are properly trained and aware of safe operations.
4-Bromo-3-fluorotoluene may be used in the preparation of 1-(4-cyano-3- fluorobenzyl)-5-imidazolecarboxaldehyde and 1-bromo-4-bromomethyl-2-fluorobenzene.
4-Bromo-3-fluorotoluene is used in the synthesis of S-trityl-L-cysteine based inhibitors that show potent antitumor activity in lung cancer models. Chemical reagent for organic synthesis.
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Product Name: | 4-Bromo-3-fluorotoluene |
Synonyms: | 4-BROMO-3-FLUOROTOLUENE;3-FLUORO-4-BROMO-TOLUENE;4-Bromo-3-fluorotoluene,98+%;4-Bromo-3-fluorotoluene 98%;4-Bromo-3-fluoro-1-methylbenzene;4-Bromo-3-flurotoluene;3-FLUORO-4-BROMO-TOLUONE;4-BroMo-3-fluorotoluene, 98% 5GR |
CAS: | 452-74-4 |
MF: | C7H6BrF |
MW: | 189.02 |
EINECS: | 629-423-4 |
Product Categories: | Halogen toluene; |
Mol File: | 452-74-4.mol |
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4-Bromo-3-fluorotoluene Chemical Properties |
Boiling point | 95 °C/50 mmHg (lit.) |
density | 1.494 g/mL at 25 °C (lit.) |
refractive index | n20/D 1.53(lit.) |
Fp | 95 °F |
storage temp. | Sealed in dry,Room Temperature |
form | Liquid |
Specific Gravity | 1.494 |
color | Clear light yellow |
BRN | 2500154 |
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