Ambroxol Hydrochloride (AmbroxolHydrochloride) is also known as bromocyclohexylamine hydrochloride, and its chemical name is trans-4-[(2-amino3,5-dibromobenzyl)amino]cyclohexanol hydrochloride, which is The active metabolite of the sputum drug bromhexine (N-desmethyl, cyclohexyl is introduced into the trans-hydroxyl group at the para position), the toxicity is lower than that of bromhexine, and the activity is higher than that of bromhexine.
1. The effect of relieving cough and resolving phlegm:
Ambroxol hydrochloride mainly acts on secretory cells in the respiratory tract, regulates the secretion of mucus and serous substances, increases the secretion of serous, and can also lyse the polysaccharide fibers of acid glycoprotein in sputum, and inhibit the acidic protein in mucous glands and goblet cells. The synthesis of sputum reduces the viscosity of sputum, makes sputum thin and easy to discharge; at the same time, the drug can also increase the frequency and intensity of the movement of respiratory tract cilia, promote sputum discharge and self-purification of the respiratory tract.
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Analysi | Specifications | |
Assay | ≥99% | |
Appearance | White powder | |
Loss on Drying | ≤1.0% | |
Ash | ≤1.0% | |
As | ≤2.0ppm | |
Pb | ≤2.0ppm | |
Insoluble impurity content | ≤0.05% | |
Total Plate Count | ≤1000 cfu/g | |
Yeast &. Mold | ≤100 cfu/g | |
E.Coli | Negative | |
Salmonella | Negative | |
Conclusion |
Conform USP Standard.
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Storage condition |
Store in cool & dry place, Keep away from strong light and heat.
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Shelf life |
2 years when properly stored.
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