Creatine phosphate is a high-energy compound, which is a temporary storage form of high-energy phosphate bonds. It can release energy during hydrolysis and improve muscle strength during exercise. It is mainly used to reduce myocardial damage and restore normal heart rhythm. Clinically, it is mainly used for myocardial deficiency. Blood, myocardial hypertrophy, myocardial infarction, heart failure and other heart diseases.
Patients with cardiomyopathy should pay attention to maintaining a good mood, regular work and rest, avoid fatigue and staying up late, exercise appropriately, do more relaxing aerobic exercise such as walking, gymnastics, and Tai Chi, avoid strenuous anaerobic exercise, and eat light and low-salt diet, which is not easy Excessive hunger and overeating, so as not to increase the burden on the heart. In a word, creatine phosphate is a commonly used cardiomyocyte protective agent in clinic, which can nourish the myocardium and is mainly used for the treatment of heart disease.
(1) the myocardial protective agent
Creatine phosphate is widely distributed in the body each organization, 90% in muscle tissue, creatine phosphate is used to maintain ATP levels.Creatine phosphate by opening synthesis pathway and reduce the rate of decomposition, protect the sarcolemma from ischemic damage and maintain cell nuclear acid storage.Clinical cardiac protection for heart disease and myocardial metabolic distress of other conditions.Suitable for the treatment of myocardial ischemia, hypertrophy, myocardial infarction and heart failure (adjuvant treatment).Can also be used for a variety of cardiac surgery.
(2) the buffer acid in muscle increased suddenly
(3) creatine phosphate (CP) is also involved in energy transport
Is the energy from the mitochondrial transport to other parts of the muscle.
(4) players preferred supplements
Creatine phosphate to increase the athletes' physical fitness, improve performance have obvious effect, safe and effective, no side effects.In the game, creatine phosphate (CP) levels increased to improve the training and competition results.
(5) the storage form of ATP
Creatine phosphate can transfer high-energy phosphate to ADP to generate ATP, therefore the creatine phosphate is the storage form of ATP.
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Items | 标准 | 结果 | |
外貌 | White or off-white crystalline powder | 符合 | |
鉴别 | By IR | 符合 | |
By HPLC | 符合 | ||
Solubility | slightly soluble in water | 符合 | |
Water Content | 3.00%~4.40% | 3.60% | |
熔点 | 69~75ºC | 73.4~74.7ºC | |
Heavy Metal | ≤20ppm | 符合 | |
Isomer | ≤0.15% | 0.03% | |
13.6%~16.6% | 15.3% | ||
Purity(HPLC) | ≥99.50% | 99.88% | |
测定 (HPLC basis on drying) |
98.0%~102.0% | 99.96% | |
Particle Size | D90: ≤50µm, D98: ≤80µm | 30µm, 38µm | |
Reference Standard | In-house Standard | ||
结论 | The product complied to In-house standard. |
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