Sodium Deoxycholate

Pharmaceutical Grade CAS 302-95-4 Sodium Deoxycholate

 

  • 產品名稱:

    Sodium Deoxycholate

  • 年級:

    Pharmaceutical Grade

  • 特性:

    白色粉末

  • 包裝:

    25kg/bag

  • 最小起訂量:

    1 ton

  • 貯存:陰涼乾燥處
  • 保存期限:2年


細節

標籤

產品描述

 

Sodium deoxycholate is a bile acid formed bybacterial action from cholate. It is usually conjugatedwith glycine or taurine. Deoxycholic acid acts as adetergent to solubilize fats for intestinal absorption, isreabsorbed itself, and is used as a choleretic anddetergent.

產品展示

 

特徵

 

1.Historically sodium deoxycholate was used as an intermediate for the production of corticosteroids, which have anti-inflammatory indications.

2. It is used in the preparation and formulation of certain microbiological diagnostic media.

An emerging use of sodium deoxycholate acid is as a biological detergent to lyse cells and solubilise cellular and membrane components.

應用

 

• Popular anionic, bile-acid detergent for many laboratory uses
• Effective in disrupting and dissociating many types of protein interaction
• Can be removed from solution by dialysis
• Useful for elution or regeneration of certain kinds of affinity columns
• High-purity compound with low UV absorptivity

 

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規格

 

物品 規格 結果
外貌 White powder, no odor and smell 白色粉末
Content (The uv method to detect) ≥ 98.0 % 98.52 %
Solubility(Solvent with water and alcohol) Clear and no deposit 符合
Arsenic salt ≤0.0002% 符合
Than the curl 40°~ 45° 43.8°
Sodium 5.0%~6.1% 5.6%
乾燥失重 5.0% 1.93%
Heavy Metal ≤20ppm 符合

 

 

產品知識:

 

In nature, sodium deoxycholate, which is referred to as a "secondary bile acid", is produced in the intestine from the salts of glycocholic and taurocholic acid (see cholic acid ) by the action of bacterial enzymes. Less than half of the sodium deoxycholate is absorbed by the intestine and is returned the liver where it is conjugated and released into the gall bladder.
Sodium deoxycholate is extracted from cattle bile(also known as "bovine bile" or "ox bile") , which is a by-product of the meat processing industry, in a high temperature alkaline process.

(1) Historically sodium deoxycholate was used as an intermediate for the production of corticosteroids, which have anti-inflammatory indications.

(2) It is used in the preparation and formulation of certain microbiological diagnostic media.

(3) An emerging use of sodium deoxycholate acid is as a biological detergent to lyse cells and solubilise cellular and membrane components.

(4) Popular anionic, bile-acid detergent for many laboratory uses

(5) Effective in disrupting and dissociating many types of protein interaction

(6) Useful for elution or regeneration of certain kinds of affinity columns

(7) It is most frequently used as a component of cell lysis buffers (e.g., RIPA buffer), but also has been used for liposome preparation, isolation of membrane proteins and lipids, preventing nonspecific binding in affinity chromatography and a cell culture media supplement.

 
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