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Dapagliflozin Propanediol Monohydrate

High Purity Dapagliflozin Propanediol Monohydrate Raw Powder CAS 960404-48-2

 

  • 產品名稱:

    Dapagliflozin Propanediol Monohydrate

  • 年級:

    Pharmaceutical grade

  • 特性:

    白色粉末

  • 包裝:

    25公斤/桶

  • 最小起訂量:

    1 kilo

  • 貯存:陰涼乾燥處
  • 保存期限:2年


細節

標籤

產品描述

Dapagliflozin is a prescription medication that is mainly used alongside diet and exercise to help treat type 2 diabetes, but it is also used in the treatment of heart failure. It was first approved by the US Food and Drug Administration (FDA) in 2014.Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. This class of drug uses the kidneys to help control your glucose (blood sugar) levels. It works by increasing the amount of glucose removed from the body when you urinate. It also reduces the amount of effort your heart has to put in to pumping blood around your body.

應用
  • Dapagliflozin is not for people with type 1 diabetes. Dapagliflozin may increase the risk of diabetic ketoacidosis (increased ketones in your blood or urine) in people with type 1 diabetes.
  • Dapagliflozin is not for use to improve blood sugar (glucose) control in adults with type 2 diabetes who have moderate to severe kidney problems, because it may not work.
  • Dapagliflozin is not for people with certain genetic forms of polycystic kidney disease, or who are taking or have recently received immunosuppressive therapy to treat kidney disease. Dapagliflozin is not expected to work if you have these conditions.
  • It is not known if dapagliflozin is safe and effective in children younger than 18 years of age.

 

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規格
Items Standards Results
外貌 White or off-white crystalline powder 符合
Identification By IR 符合
  By HPLC 符合
Solubility Highly soluble in methanol,soluble in
ethanol,acetonitrile; slightly soluble in water
符合
Water Content 3.00%~4.40% 3.60%
熔點 69~75ºC 73.4~74.7ºC
Heavy Metal ≤20ppm 符合
Isomer ≤0.15% 0.03%
Propylene Glycol Content 13.6%~16.6% 15.3%
Residual Solvents Ethanol: ≤1000ppm ND
  Ethyl acetate: ≤1000ppm ND
  Dichloromethane: ≤120ppm ND
  Hexane: ≤600ppm 68ppm
Related Substances Any Single Impurities: ≤0.10% 0.05%
  Total Impurities: ≤0.50% 0.12%
Purity(HPLC) ≥99.50% 99.88%
測定
(HPLC basis on drying)
98.0%~102.0% 99.96%
Particle Size D90: ≤50µm, D98: ≤80µm 30µm, 38µm
Reference Standard In-house Standard
結論 The product complied to In-house standard.

 

 

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Accepted Payment Currency:USD;EUR
接受的付款方式:T/T、西聯匯款;貝寶,貿易保證。
使用語言:英語。

 

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