H-indazole-3-carboxylate (1H-indazole-3-carboxylate) is an organic compound.
Properties: It is soluble in organic solvents such as acetonitrile, dichloromethane and ethanol, but insoluble in water.
Preparation:
1H-indazole-3-carboxylate methyl ester can be prepared by various synthetic methods. The more common method is to react indazole-3-carboxylic acid with methanol under acid catalysis. The specific steps involve reacting indazole-3-carboxylic acid with a small amount of acid (such as sulfuric or hydrochloric acid) and methanol at the appropriate temperature for a period of time, and then purifying the product by distillation.
Safety information:
1H-indazole-3-carboxylate methyl ester is generally considered to be relatively safe under correct operating conditions. However, as chemicals, general laboratory safety practices should be followed. It can be irritating to the eyes, skin, and respiratory system, and should be handled with personal protective equipment such as lab gloves, protective glasses, and a lab coat. Ingestion and inhalation should be avoided.
Indazole-3-carboxylic Acid Methyl Ester has potential as application of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase. Also used in the preparation of indazole-pyridine based protain kinase/Akt inhibitors.
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Product Name: | 1H-indazole-3-carboxylic acid methyl ester |
Synonyms: | 1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER;3-Indazolecarboxylic acid methyl ester;methyl 1H-indazole-3-carboxylate(SALTDATA: FREE);Methyl 1H-indazole-3-carb...;1H-Indazole-3-Carboxylic Acid Methyl Ester(WX6;Indazole-3-carboxylic Acid Methyl Ester;TIMTEC-BB SBB009999;METHYL INDAZOLYL-3-CARBOXYLATE |
CAS: | 43120-28-1 |
MF: | C9H8N2O2 |
MW: | 176.17 |
EINECS: | 251-228-4 |
Product Categories: | |
Mol File: | 43120-28-1.mol |
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1H-indazole-3-carboxylic acid methyl ester Chemical Properties |
熔點 | 162-163℃ |
沸點 | 345.2±15.0 °C(Predicted) |
密度 | 1.324 |
儲存溫度 | Sealed in dry,Room Temperature |
溶解度 | Chloroform (Slightly), Methanol (Slightly) |
形式 | Solid |
pka | 11.93±0.40(Predicted) |
顏色 | White to Off-White |
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