H-indazole-3-carboxylate (1H-indazole-3-carboxylate) is an organic compound.
Properties: It is soluble in organic solvents such as acetonitrile, dichloromethane and ethanol, but insoluble in water.
Preparation:
1H-indazole-3-carboxylate methyl ester can be prepared by various synthetic methods. The more common method is to react indazole-3-carboxylic acid with methanol under acid catalysis. The specific steps involve reacting indazole-3-carboxylic acid with a small amount of acid (such as sulfuric or hydrochloric acid) and methanol at the appropriate temperature for a period of time, and then purifying the product by distillation.
Safety information:
1H-indazole-3-carboxylate methyl ester is generally considered to be relatively safe under correct operating conditions. However, as chemicals, general laboratory safety practices should be followed. It can be irritating to the eyes, skin, and respiratory system, and should be handled with personal protective equipment such as lab gloves, protective glasses, and a lab coat. Ingestion and inhalation should be avoided.
Indazole-3-carboxylic Acid Methyl Ester has potential as application of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase. Also used in the preparation of indazole-pyridine based protain kinase/Akt inhibitors.
Anyị nwere ọtụtụ ụlọ ọrụ dị elu nke nwere nkwado miri emi, nke nwere ike inye gị ngwaahịa dị elu na ọnụ ahịa asọmpi. Anyị nwekwara ike inye ego maka nnukwu ịzụrụ ihe. Anyị na-akwado ọtụtụ ụlọ ọrụ na-ebuga ibu ndị ọkachamara, nwere ike ịnapụta ngwaahịa n'enweghị nsogbu na aka gị. Oge nnyefe bụ ihe dịka ụbọchị 3-20 mgbe nkwenye nke ịkwụ ụgwọ gasịrị.
Product Name: | 1H-indazole-3-carboxylic acid methyl ester |
Synonyms: | 1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER;3-Indazolecarboxylic acid methyl ester;methyl 1H-indazole-3-carboxylate(SALTDATA: FREE);Methyl 1H-indazole-3-carb...;1H-Indazole-3-Carboxylic Acid Methyl Ester(WX6;Indazole-3-carboxylic Acid Methyl Ester;TIMTEC-BB SBB009999;METHYL INDAZOLYL-3-CARBOXYLATE |
CAS: | 43120-28-1 |
MF: | C9H8N2O2 |
MW: | 176.17 |
EINECS: | 251-228-4 |
Product Categories: | |
Mol File: | 43120-28-1.mol |
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1H-indazole-3-carboxylic acid methyl ester Chemical Properties |
Ebe mgbaze | 162-163℃ |
Ebe esi nri | 345.2±15.0 °C(Predicted) |
njupụta | 1.324 |
nchekwa okpomọkụ. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Methanol (Slightly) |
ụdị | Solid |
pka | 11.93±0.40(Predicted) |
agba | White to Off-White |
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