High Purity Hot Selling CAS 50-78-2 Bulk Aspirin Powder

Aspirin (acetyl salicylic acid) is a white crystalline or crystalline powder, odorless or slightly acetic acid odor, slightly soluble in water, soluble in ethanol, soluble in ether, chloroform, aqueous solution is acidic. This product is a derivative of salicylic acid, after nearly a hundred years of clinical application, proved to relieve mild or moderate pain, such as toothache, headache, neuralgia, muscle pain and dysmenorrhea effect is good, also used for cold, flu and other febrile diseases fever, rheumatic pain, etc. In recent years, it has been found that aspirin has an inhibitory effect on platelet aggregation and can prevent thrombosis. It is clinically used to prevent thrombosis after transient ischemic attack, myocardial infarction, artificial heart valve, venous fistula or other operations.
Analgesic action - mainly by inhibiting the synthesis of prostaglandins and other substances that can make pain sensitive to mechanical or chemical stimuli (such as bradykinin, histamine), which is a peripheral analgesic. But the possibility of central analgesia cannot be ruled out. It is effective for chronic dull pain, but not for acute acute pain and severe pain.
Antipyretic effect: It can reduce the body temperature of patients with fever, but has no effect on normal body temperature. It may cause peripheral vascular dilation by acting on the hypothalamus thermoregulatory center, increase skin blood flow, sweat, and increase heat dissipation, which plays an antipyretic effect. This central effect may be related to the inhibition of the synthesis of prostaglandins in the hypothalamus.
Anti-inflammatory, anti-rheumatic - The mechanism of its anti-inflammatory action is not well understood, but may be due to its action on inflammatory tissues, by inhibiting the synthesis of prostaglandins or other substances that can cause an inflammatory response (such as histamine). Regarding its anti-rheumatism, mainly because it has antipyretic, analgesic and anti-inflammatory effects.
Antiplatelet aggregation - Aspirin acts as an antiplatelet aggregator by inhibiting platelets' prostaglandin epoxidase, thereby preventing thromboxane A2 production.
Similar to diabetes - aspirin may promote endogenous insulin secretion and liver glycogen synthesis, inhibit the absorption of sugar by the intestine and promote the uptake of sugar by tissues, thus playing a role in lowering blood sugar.
For Alzheimer's disease (Alzheimer's disease) - Studies have found that elderly people who regularly take aspirin have a significantly reduced risk of dementia and cognitive impairment. Low-dose aspirin can reduce the progression of Alzheimer's disease. This is because aspirin enhances blood flow to the brain and prevents blood clotting.
Reduce the incidence and mortality of gastrointestinal malignancy - Studies have shown that PGE2 is closely related to the development and metastasis of tumors, and its level increases gradually with tumor growth. Aspirin can reduce the level of PGE2 and inhibit tumor growth and metastasis. The synthesis of TXA2 in tumor tissue is increased, and aspirin is obviously significant in preventing hypercoagulability in tumor patients, and has anti-tumor metastasis effect. Aspirin therapy for 5 years or more: 35 percent lower risk of 20-year death from gastrointestinal cancer.
Reducing ototoxic antibiotics for Hearing impairment - Animal studies have shown that aspirin combined with aminoglycoside antibiotics reduces the incidence of hearing impairment. When aminoglycoside antibiotics enter the body, they combine with iron to form free radicals, which can damage hair cells. When hair cells are damaged, the inner ear loses its ability to detect sound, resulting in permanent hearing loss. Aspirin is broken down into salicylate, which blocks the formation of free radicals, thereby reducing the incidence of antibiotics-induced deafness.
Aspirin is a long-established antipyretic and analgesic. Aspirin is widely used in the treatment of fever, headache, neuralgia, muscle pain, rheumatic fever, acute rheumatoid arthritis, etc., because it is easily absorbed by oral administration, widely distributed in the body tissues and has a strong effect. With the widespread use of aspirin, its adverse reactions are gradually increasing, so when using aspirin to treat various diseases, it is necessary to closely monitor its adverse reactions.