Amoxicillin, an organic compound with the chemical formula C16H19N3O5S, is one of the most commonly used semi-synthetic penicillin-based broad-spectrum β-lactam antibiotics, amoxicillin has a strong bactericidal effect and a strong ability to penetrate cell membranes.
Amoxicillin is suitable for the following infections caused by sensitive bacteria (strains that do not produce beta-lactamase) :
1, hemolytic streptococcus, streptococcus pneumoniae, staphylococcus or haemophilus influenzae caused by otitis media, sinusitis, pharyngitis, tonsillitis and other upper respiratory tract infections;
2. Urogenital tract infection caused by Escherichia coli, Proteus mirabilis or Enterococcus faecalis;
3. Skin and soft tissue infections caused by hemolytic streptococcus, staphylococcus or Escherichia coli;
4. Lower respiratory tract infections such as acute bronchitis and pneumonia caused by hemolytic streptococcus, streptococcus pneumoniae, Staphylococcus or Haemophilus influenzae;
5, acute simple gonorrhea;
6, can be used to treat typhoid fever, other salmonella infections, typhoid carriers and leptospirosis; Amoxicillin can also be combined with clarithromycin and Lansoprazole to eradicate Helicobacter pylori in stomach and duodenum and reduce the recurrence rate of gastrointestinal ulcer.
Sinemizi-mveliso emininzi ekumgangatho ophezulu enentsebenziswano enzulu, enokubonelela ngeemveliso ezikumgangatho ophezulu kunye namaxabiso akhuphisanayo. Kwaye sinako ukunika izaphulelo zokuthengwa kwezinto ezininzi.Kwaye siyasebenzisana neenkampani ezininzi zokuthunyelwa kwempahla, zinokuzisa iimveliso ngokukhuselekileyo nangokutyibilikayo ezandleni zakho. Ixesha lokuhambisa limalunga neentsuku ezi-3-20 emva kokuqinisekiswa kwentlawulo.
Tests | Iinkcukacha | Iziphumo | |
Imbonakalo | White or almost white powder, hygroscopic | Almost white powder, hygroscopic | |
Ukuchongwa | (l)HPLC: positive | Positive | |
(2) Reaction (b) of potassium: positive | Positive | ||
(3) Reaction of cellulose: positive | Positive | ||
pH | 4.8 - 8.0 | 5.7 | |
Polymeric impurities and other impurities absorbing at 278 nm | NMT 0.40 | 0.033 | |
Water | NMT2.5% | 0.46% | |
Related substances | Impurity E: NMT 1.0% | 0.014% | |
Impurity G: NMT 1.0% | 0.0017% | ||
Any other single impurity (major): NMT 0.10% | <0.05% | ||
Total impurities: NMT 2.0% | 0.016% | ||
Assay (HPLC) | 91.2% ~107.1% (as content of potassium clavulanate stated on the label) | 100.4% | |
CLAV.ACID(as is)38.3%~45.0% | 42.1% | ||
CLAV. POT. (as is)45.6%~53.5% | 50.2% | ||
Ukuqukumbela | Conforms to the requirements of EP. |
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