Guanidine Hydrochloride

Guanidine hydrochloride is an organic substance with the chemical formula CH6ClN3 and is a white or yellowish lump. Used as an intermediate in medicine, pesticides, dyes and other organic compounds, it is an important raw material for the manufacture of sulfonamides and folic acid, and can also be used as an antistatic agent for synthetic fibers.

1. Properties: white or yellowish clumps.

2. Melting point (℃) : 181-183.

3. Relative density (g/mL,20/4℃) : 1.354.

4. Solubility: 228g can be dissolved in 100g of water at 20℃, 76g can be dissolved in 100g of methanol, and 24g can be dissolved in 100g of ethanol. Almost insoluble in acetone, benzene and ether.

5.pH value (4% aqueous solution,25℃) : 6.4.

1. It can be used as intermediates in medicine, pesticides, dyes and other organic synthesis. It can be used to synthesize 2-aminopyrimidine, 2-amino-6-methylpyrimidine, 2-amino-4, 6-dimethylpyrimidine, and is an intermediate in the manufacture of sulfadiazine, sulfadimethyrimidine, sulfadimethyrimidine and other sulfonamide drugs.

2. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate to form 2, 4-diamino-6-hydroxypyrimidine, which is used to synthesize folic acid, an anti-anemia drug. It can also be used as an antistatic agent for synthetic fibers.

3. It can also be used as protein denaturant.

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This product is more unstable, in aqueous solution can be hydrolyzed to produce ammonia and urea, so its toxicity and urea is the same, guanidine and its derivatives are generally more toxic than urea.

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