Glucagon Acetate

Glucagon is a hormone secreted along with insulin by the islet alpha cells of the vertebrate pancreas. Glucagon works against insulin and increases blood sugar. The main diseases detected by glucagon include children's hypoglycemia, elderly hypoglycemia, chronic pancreatitis, islet cell tumor, diabetes, coronary heart disease, glucagon tumor and so on.

The chemical nature of glucagon, a hormone usually secreted by the alpha cells of the pancreatic islets.

Glucagon is a hormone mainly secreted by human islet α cells, which has the function of increasing blood sugar and promoting lipolysis, and mostly antagonizes insulin. It mainly raises blood sugar by promoting glycogenolysis and promoting gluconeogenesis, but glucagon can also break down glucose from liver glycogen by activating phosphorylase in liver cells.

Glucagon and insulin are in a relatively balanced state, with insulin mainly lowering blood sugar and glucagon mainly increasing blood sugar. If insulin secretion increases, glucagon also increases, which keeps blood sugar in the normal range. For example, fasting fluctuations are about 3-6 mmol/L and postprandial fluctuations are about 4-8mmol/L to avoid various effects on tissues caused by high or low blood sugar.

If glucagon is abnormal, it will generally be manifested as hypoglycemia, obesity, and some patients may develop acanthosis nigricans. Patients should seek medical attention in time and carry out standardized treatment to avoid blind adjustment of insulin dose.

Glucagon is a hormone that promotes catabolism. It promotes hepatic glycogenolysis and gluconeogenesis, and increases blood sugar significantly. Promote lipolysis and fatty acid oxidation; Accelerate the entry of amino acids into liver cells and provide raw materials for gluconeogenesis. Blood glucose concentration is also the main factor regulating the secretion of glucagon. Blood glucose decreased, glucagon secretion increased, vice versa; Insulin can indirectly promote the secretion of glucagon by lowering blood sugar, or directly inhibit the secretion of adjacent A cells through paracrine mode. The sympathetic nerve promotes glucagon secretion, while the vagus nerve inhibits it.

The factories we cooperate with have large shipments of Glucagon Acetate, rapid delivery and fresh production dates. This can help some suppliers and buyers to buy high-quality Glucagon Acetate with fresh production date from us. We will not sell products near the expiration date to customers like others, because transportation takes time, so our delivery cycle is usually arranged in 10-15 days, and orders under 10 tons will be shipped within 10 days.

Glucagon can promote glycogenolysis and gluconeogenesis, promote lipolysis, and promote the secretion of insulin and islet somatostatin.

1. 1.Promoting the role of glycogenolysis and gluconeogenesis: Promoting the role of glycogenolysis and gluconeogenesis can significantly increase blood sugar, which is also the most important role, and can be used for hypoglycemia.

2. 2.Promote the role of lipolysis: can activate lipase, promote lipolysis, but also strengthen fatty acid oxidation, so that ketone body production increased. The target organ for these metabolic effects of glucagon is the liver, and these effects disappear when the liver is removed or blood flow to the liver is blocked.

3. 3.Promote the secretion of insulin and islet somatostatin: against insulin, and insulin forms a negative feedback regulatory loop between blood sugar levels.