Peganumharmala, commonly referred to as "Syrian rue", is native to China, east of the Eastern Mediterranean region to India and the western United States. This perennial herb has been shown to grow spontaneously in arid and rocky areas.
Peganumharmala contains β-carboline alkaloids (or harmala alkaloids), which are toxic to humans and animals. These compounds have known hallucinogens and strong monoamine oxidase (MAO) inhibitory activity.
Psychoactive effects: Harmaline has psychoactive effects and has been used in traditional medicine and shamanic rituals by indigenous cultures in South America and the Middle East. It is believed to produce a hallucinogenic effect when ingested, and is sometimes used as a substitute for the more potent hallucinogen DMT.
Anti-depressant and anxiolytic effects: Harmaline has been found to have anti-depressant and anxiolytic effects in animal studies. It may help regulate the levels of certain neurotransmitters, such as serotonin and dopamine, which are involved in mood regulation.
Anti-cancer activity: Harmaline has been found to have anti-cancer activity in laboratory studies. It may help induce apoptosis, or programmed cell death, in cancer cells, and may enhance the effectiveness of chemotherapy drugs.
Anti-inflammatory activity: Harmaline has been found to have anti-inflammatory properties, which may help reduce inflammation in the body. This is believed to be due to its ability to inhibit the production of pro-inflammatory cytokines and enzymes.
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Physical-chemical Index |
|
Chemical formula |
C13H12N2O |
Cas No. |
442-51-3 |
Assay (HPLC) |
98% Min |
Particle Size |
98% pass 80 mesh |
Loss on drying |
5% Max |
Ash |
5% Max |
Heavy metals |
10ppm Max |
Lead |
2ppm Max |
Arsenic |
2ppm Max |
Mercury |
1ppm Max |
Cadmium |
1ppm Max |
Hygienic Index |
|
Total plate count |
1,000cfu/g Max |
Mold & yeast |
100cfu/g Max |
E.Coli |
Negative |
Salmonella |
Negative |
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