The chemical structure of tranexamic acid is similar to lysine, competitive inhibition of plasmin original in fibrin adsorption, to prevent their activation, protection fiber protein not to degrade by plasmin and dissolve, eventually achieve hemostasis. Applicable in the treatment of acute or chronic, localized or systemic primary fiber fibrinolytic hyperthyroidism caused by bleeding, such as obstetric hemorrhage, renal hemorrhage, hemorrhage of hypertrophy of the prostate, hemophilia, pulmonary tuberculosis hemoptysis, stomach bleeding, after operation of liver, lung, spleen and other viscera hemorrhage; also can be used in surgery when abnormal bleeding etc..
Clinical tranexamic acid has effect significantly to insect bites disease, dermatitis and eczema, simple purpura, chronic urticaria, artificial sex urticaria, toxic eruption and eruption. And also has a certain effect on erythroderma, scleroderma, systemic lupus erythematosus (SLE), Erythema multiforme, shingles and alopecia areata. Treatment of hereditary angioedema effect is also good. In the treatment of Chloasma, general medicine is effective about 3 weeks, markedly effective 5 weeks, a course of 60 days. Given orally in doses of 0.25 ~ 0.5 g, a day 3 ~ 4 times. A few patients can nausea, fatigue, pruritus, abdominal discomfort, and diarrhea side effects after withdrawal symptoms disappear.
1.Tranexamic acid is mainly used for various types of bleeding caused by acute or chronic, localized or systemic fibrinolysis.
2. The melamine-removing effect of tranexamic acid is about 50 times higher than vitamin C and nearly 10 times that of fruit acid, so it can also be used for skin whitening.
3. Pay attention to the secondary high fibrinolysis state caused by disseminated intravascular coagulation, and use this product with caution before heparinization.
Re na le lifeme tse ngata tsa boleng bo holimo tse nang le tšebelisano e tebileng, tse ka u fang lihlahisoa tsa boleng bo holimo le litheko tsa tlholisano. Hape re ka fana ka litheolelo bakeng sa ho reka ka bongata.'Me re sebelisana le lik'hamphani tse ngata tsa litsebi tse tsamaisang thepa, li ka isa lihlahisoa ka mokhoa o sireletsehileng le ka thelelo matsohong a hau. Nako ea ho fana e ka ba matsatsi a 3-20 ka mor'a hore ho netefatsoe tefo.
Ntho | Tlhaloso | Test Results |
Ponahalo | White powder, neutral odor, highly hygroscopic | Ikamahanya |
Boitsebiso | TLC:Standard solution and test solution same spot,RF | Ikamahanya |
Assay (Dry Basis) | 98.0%--102.0% | 100.98% |
Specific Optical | -2.4°~ -2.8° | -2.71° |
PH | 4.5~7.0 | 5.3 |
Heavy Metals (As Pb) | ≤10ppm | <10ppm |
Joalo ka | ≤1ppm | Not Detected |
Pb | ≤0.5ppm | Not Detected |
Cd | ≤1ppm | Not Detected |
Hg | ≤0.1ppm | Not Detected |
Related substance | Spot not bigger than standard solution spot |
No spot |
Residual solvent | <0.5% | E lumellana |
Water Content | <2% | 0.18% |
Tranexamic acid is a White or almost white, crystalline powder. It is freely soluble in water and in glacial acetic acid and is very slightly soluble in ethanol and practically insoluble in ether. Tranexamic acid is an antifibrinolytic agent and is commonly used for heavy menstrual bleeding. Tranexamic acid is a monocarboxylic acid. It has a role as an antifibrinolytic drug and a hematologic agent. It is functionally related to a cyclohexanecarboxylic acid.
Uses
Fibrinolysis, the cleavage of fibrin by plasmin, is a normal step in the dissolution of fibrin clots after wound repair. Tranexamic acid is an inhibitor of fibrinolysis that blocks the interaction of plasmin with fibrin (IC50 = 3.1 μM). It is a lysine mimetic that binds the lysine binding site in plasmin. Antifibrinolytic agents have value when fibrinolytic activity is abnormally high or when coagulation is impaired.
Various bleedings caused by acute or chronic, localized or systemic primary hyperfibrinolysis; secondary hyperfibrinolytic state caused by disseminated intravascular coagulation. Generally do not use this product before heparinization.
Trauma or surgical bleeding in tissue and organs with abundant plasminogen activators such as prostate, urethra, lung, brain, uterus, adrenal glands, and thyroid.
1. Na u feme kapa k'hamphani ea khoebo?
Re komnay e kopanyang indasteri le khoebo, ho fana ka ts'ebeletso e le 'ngoe.OEM e ka amoheloa.
2. O fana ka mehlala? Na ke mahala kapa ho feta?
Mehlala ea mahala. Tefiso ea thepa ea sampole e hloka ho lefuoa ka lehlakore la hau.
3. O na le litifikeiti tse amanang le taolo ea boleng?
Setifikeiti sa ISO 9001:2008 ho netefatsa boleng.
4. Ke fane ka eng ho fumana khotheishene?
Pls re tsebise ka mofuta oa sehlahisoa seo u se hlokang, bongata ba odara, aterese le litlhoko tse ikhethileng. Khotheishene e tla etsoa bakeng sa referense ea hau ka nako.
5. U khetha mofuta ofe oa mokhoa oa ho lefa? Ke mantsoe a mofuta ofe a amoheloang?
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