Paracetamol, the international non-proprietary drug name paracetamol. It is the most commonly used non-anti-inflammatory antipyretic analgesic drug, antipyretic effect is similar to aspirin, the analgesic effect is weak, no anti-inflammatory and anti-rheumatic effect, is the best variety of acetanilide drugs. It is especially suitable for patients who cannot use carboxylic acids. For cold, toothache and other diseases. Acetaminophen is also an organic synthetic intermediate, a stabilizer of hydrogen peroxide, and a photographic chemical.
Acetaminophen, prism crystal from ethanol. Melting point 169-171℃, relative density 1.293(21/4℃). Soluble in ethanol, acetone and hot water, insoluble in water, insoluble in petroleum ether and benzene. No smell, bitter taste. The pH of saturated aqueous solution is 5.5-6.5.
By inhibiting cyclooxygenase, selective inhibition of prostaglandin synthesis in hypothalamic thermoregulatory center leads to peripheral vascular dilation and sweating, thus achieving antipyretic effect, which is similar to aspirin. It plays an analgesic role by inhibiting the synthesis and release of prostaglandins, etc. and raising the pain threshold. It is a peripheral analgesic drug with a weaker effect than aspirin and is only effective for light and moderate pain. This product has no obvious anti-inflammatory effect.
It is suitable for relieving mild to moderate pain, such as fever, headache, joint pain, neuralgia, migraine and dysmenorrhea caused by cold. It can not be used to replace aspirin or other non-steroidal anti-inflammatory drugs in the treatment of various types of arthritis because it can only relieve symptoms and has no or very little anti-inflammatory effect, and can not eliminate the redness, swelling and mobility disorders caused by arthritis. However, the product can be used for aspirin allergy, intolerance or not suitable for the use of aspirin cases, such as chickenpox, hemophilia and other bleeding diseases (including the use of anticoagulant treatment cases), as well as peptic ulcer, gastritis and so on.
Re na le lifeme tse ngata tsa boleng bo holimo tse nang le tšebelisano e tebileng, tse ka u fang lihlahisoa tsa boleng bo holimo le litheko tsa tlholisano. Hape re ka fana ka litheolelo bakeng sa ho reka ka bongata.'Me re sebelisana le lik'hamphani tse ngata tsa litsebi tse tsamaisang thepa, li ka isa lihlahisoa ka mokhoa o sireletsehileng le ka thelelo matsohong a hau. Nako ea ho fana e ka ba matsatsi a 3-20 ka mor'a hore ho netefatsoe tefo.
Hebei Disha Import and Export Trade Co., Ltd.
TS'ELISO TS'ELISO
Ponahalo |
White or almost white ,crystalline powder. |
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Boitsebiso |
A:IR absorption |
E lumellana |
B:UV absorption |
E lumellana |
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C:TLC |
E lumellana |
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Sebaka se qhibilihang |
168~172°C |
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Water |
Not more than0.5% |
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Related substance |
Impurity(chloroacetanilide)not more than 10 ppm |
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Impurity K(4-aminophenol)not more than 50 ppm |
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Impurity F(4-nitrophenol)not more than 0.05% |
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any other impurity not more than 0.05% |
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Total of other impurities not more than 0.1% |
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Residue on ignition |
Not more than 0.1% |
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Chloride |
Not more than 0.014% |
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Sulfate |
Not more than 0.02% |
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Sulfide |
E lumellana |
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Heavy metals |
Not more than 0.001% |
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Free p-aminophenol |
Not more than 0.005% |
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Limit of P-chloroacetanilide |
Not more than 0.001% |
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Readily carbonizable substances |
E lumellana |
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Residual solvents |
Residual content of acetic acid is limited by the test of loss on dryingnot more than0.5% |
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Assay(anhydrous basis) |
99.0~101.0% |
Sehlahisoa see ke eng?
Paracetamol powder nutritional supplemen Mainly used for amino acid infusion,due to special wettability, also used in cold cream,osmetics. Serine constitute the human body of several kinds of essential amino acid of protein a, for the construction of protein has a very important role.
Lihlopha tsa lihlahisoa