Ivermectin is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod,
canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum resistant parasites.
Ivermectin for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae
effectively, but for adult worms; For only in intestinal fecal round worms are also effective.
Ivermectin has the selective inhibitory effect, with no spinal nerve cells and muscle cells in the animal glutamic acid ion channels of the valve is the high binding affinity, leading to the proliferation of the chloride ion permeability of cell membrane, cause nerve cells or muscle cells hyperpolarization, parasites paralysis or death.
1. Ivermectin is the derivatives of abamectin. Ivermectin belongs to semisynthetic broad-spectrum resistant parasites.
2. Ivermectin has effect for most of the various life cycle nematodes.
3. Ivermectin has effect for the microfilaria of onchocerca volvulus,but it does not has effect for the adult onchocerca volvulus.
4. Ivermectin has effect for dung round worms that is only stay in intestinal tract.
5. Ivermectin has selective inhibition.
6. Ivermectin can not go through the blood brain barrier of humanbeings.
In veterinary medicine ivermectin powder is used against many intestinal worms (but not tapeworms), most mites, and some lice. Despite this, it is not effective for eliminating ticks, flies, flukes, or fleas. It is effective against larval heartworms, but not against adult heartworms, though it may shorten their lives. The dose of the medicine must be very accurately measured as it is very toxic in over-dosage.
It is sometimes administered in combination with other medications to treat a broad spectrum of animal parasites. Some dog breeds (especially the Rough Collie, the Smooth Collie, the Shetland Sheepdog, and the Australian Shepherd), though, have a high incidence of a certain mutation within the MDR1 gene (coding for P-glycoprotein); affected animals are particularly sensitive to the toxic effects of ivermectin.
Clinical evidence suggests kittens are susceptible to ivermectin toxicity. A 0.01% ivermectin topical preparation for treating ear mites in cats (Acarexx) is available.
Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray. While this works well in some cases, care must be taken, as several species of reptiles are very sensitive to ivermectin. Use in turtles is particularly contraindicated.
Waxaan leenahay warshado badan oo tayo sare leh oo leh iskaashi qoto dheer, kuwaas oo ku siin kara alaab tayo sare leh iyo qiimo tartan leh. Waxaan sidoo kale ku siin karnaa qiimo-dhimis iibsasho badan. Oo waxaanu la shaqaynaa shirkado badan oo soo gudbiya xamuulka, waxaanu u gaarsiin karnaa alaabta si badbaado leh oo qumman gacmahaaga. Waqtiga bixinta waa qiyaastii 3-20 maalmood kadib xaqiijinta lacag bixinta.
Tests | Tilmaamid | Natiijooyinka | |
Muuqashada | White or yellowish-white crystalline powder, slightly hygroscopic. | Yellowish-white crystalline powder, slight hygroscopic. | |
Solubility | Practically insoluble in water, soluble in alcohol. | Qualified | |
Aqoonsiga | IR | Corresponds to that of CRS standard | Qualified |
HPLC | The retention time for H2Bla and H2Blb in the chromatogram obtained with the test solution corresponds to those of standard preparation | Qualified | |
Appearance of solution | Clear and not more intensely colored than BY? | Cad | |
Specific optical rotation (anhydrous and solvent-free substance), ° | -20--17 | -17.9 | |
Related substances (%) | Individual impurity(RRT 1.3-1.5)≤2.5 | I-l:<0.05 K:2.1 | |
Any other impurity ≤ 1 | C:0.06 A:0.57 J:0.14 H:0.39 D:<0.05 F:<0.05 E:0.36 1-2:0.19 |
||
Total ≤5 | 3.8 | ||
Disregard limit: 0.05 | |||
Ethanol and Formamide (%) | Ethanol ≤5.0 | 3.9 | |
Formamide≤3.0 | 2.5 | ||
Catalyst (ug/g) | ≤1 | <1 | |
Water (%) | ≤1.0 | 0.26 | |
Sulphated ash (%) | ≤0.1 | 0.07 | |
Heavy Metal (%) | ≤0.002 | <0.002 | |
Assay (%) (HPLC, on dry basis) | H2Bla/(H2Bla +H2Blb)≥90.0 | 97.7 | |
95.0≤H2Bla +H2Blb≤ 102.0 | 96.7 | ||
Gabagabo | Complies with the requirements of EP10.0 |
Ivermectin powder is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry.
1. Ivermectin is the derivatives of abamectin. Ivermectin belongs to oral semisynthetic broad-spectrum drug resistant parasites.
2. Ivermectin has effect for most of the various life cycle nematodes.
3. Ivermectin has effect for dung round worms that is only stay in intestinal tract.
4. Ivermectin has selective inhibition.
5. Ivermectin can not go through the blood brain barrier of humanbeings.
1. Ma waxaad tahay warshad ama shirkad ganacsi?
Waxaan nahay shirkad isku-dhafan oo warshado iyo ganacsi ah, oo bixisa adeeg hal-joojin ah. OEM waa la aqbali karaa.
2. Ma bixisaa muunado? Ma bilaash baa mise waa dheeraad?
Muunado bilaash ah. Kharashka xamuulka ee muunada waxa loo baahan yahay in dhinacaaga laga bixiyo.
3. Ma haysaa wax shahaado ah oo la xidhiidha ilaalinta tayada?
ISO 9001: 2008 shahaado si loo hubiyo tayada.
4. Maxaan bixiyaa si aan u helo xigasho?
Pls noo soo sheeg nooca badeecada aad u baahan tahay, dalbo tirada, ciwaanka iyo shuruudaha gaarka ah
5. Habka lacag-bixinta noocee ah ayaad doorbidaysaa? Waa maxay nooca shuruudaha la aqbalo?
Shuruudaha keenista la aqbalay: FOB, CFR, CIF, EXW;
Lacagta Bixinta La Oggolyahay: USD;
Nooca Lacag-bixinta La Aqbalay: T/T,Ururka Galbeedka; Paypal, Hubinta Ganacsiga.
Luuqadaha lagu hadlo: Ingiriis.
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