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Aminophylline

Factory Supply High Quality Aminophylline CAS 317-34-0

 

Product name:                  Aminophylline

Grade:                             Medical Grade

Properties:                       White powder

Packing:                           25kg/Drum

Storage:                           Cool Dry Place

Shelf life:                          2 years



Faahfaahin

Tags

Sharaxaada Alaabta

 

Aminophylline is a compound of the bronchodilator theophylline with ethylenediamin in 2:1 ratio.Aminophylline is less potent and
shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD


Aminophylline is a compound salt of theophylline and ethylenediamin. Its pharmacological action mainly comes from theophylline,and  ethylenediamin enhances its water solubility. Insoluble in metha, ethanol, ether. This product has direct relaxation effect on respiratory tract smooth muscle, and its mechanism of action is relatively complex.Aminophylline is a compound of the bronchodilator theophylline with ethylenediamin in 2:1 ratio.Aminophylline is less potent and shorter-acting than theophylline. Its most common use is in the treatment of airway obstruction from asthma or COPD.
Aminophylline can be used as dicuretic and the medicine helping to relax the smooth muscle .The aminophylline can relax the bronchus and the smooth muscle of the blood vessel,inhibit the kidney tubules to reabsorb the sodium and the water and enhance the extraction of heart oedema and so on .It is usually used as mono-medicine.It is mainly used in medicine field.

 

Bandhiga alaabta

 

Astaamaha

 

Aminophylline is a nonselective adenosine receptor antagonist and phosphodiesterase inhibitor capable of reversing ischemia-induced bradyasystole. It does this by improving the rate of return of spontaneous circulation (ROSC). During atropine-resistant out-of-hospital cardiac arrest, all aspects of attempted resuscitation must proceed in accordance with standard Advanced Cardiac Life Support (ACLS) guidelines.

 

Codsiga

 

Aminophylline can be used as dicuretic and the medicine helping to relax the smooth muscle .The aminophylline can relax the bronchus and the smooth muscle of the blood vessel,inhibit the kidney tubules to reabsorb the sodium and the water and enhance the extraction of heart oedema and so on .It is usually used as mono-medicine.It is mainly used in medicine field.

Mainly used for asthma, bronchial asthma and chronic bronchitis can also be used for acute heart failure, cardiac asthma, and biliary colic, etc.
Aminophylline is a drug combination consisting of bronchodilator theophylline and ethylenediamin in 2: 1 ratio. It is a kind of non-selective adenosine receptor blocker, histone deacetylase activator and phosphodiesterase inhibition. It is mainly indicated for the treatment of various kinds of lung diseases including asthma, COPD, chronic bronchitis and emphysema. Aminophylline exerts its effect through the component of theophylline in vivo. Theophylline can relax the smooth muscle of the bronchial airways and pulmonary blood vessels. It can competitively inhibits type III and type IV phosphodiesterase (PDE), which breaks down cyclic AMP in smooth muscle cells, possibly leading to bronchodilation. Theophylline also binds to the adenosine A2B receptor to block the adenosine mediated bronchoconstriction. Furthermore, during the inflammatory states, theophylline can activate the histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones to initiate the transcription.

 

Faa'iidooyinka

 

Waxaan leenahay warshado badan oo tayo sare leh oo leh iskaashi qoto dheer, kuwaas oo ku siin kara alaab tayo sare leh iyo qiimo tartan leh. Waxaan sidoo kale ku siin karnaa qiimo-dhimis iibsasho badan. Oo waxaanu la shaqaynaa shirkado badan oo soo gudbiya xamuulka, waxaanu u gaarsiin karnaa alaabta si badbaado leh oo qumman gacmahaaga. Waqtiga bixinta waa qiyaastii 3-20 maalmood kadib xaqiijinta lacag bixinta.

 

Tilmaamid

 

Shayga

Heerka

Natiijo

Astaamaha

A white or yellowish powder, granular

White powder

Aqoonsiga

Positive reaction

Positive reaction

Appearance     of solution

Meets the requirements

U hogaansama

Biraha culus

≤20ppm

20ppm

Related substances

≤0.5%

0.50%

Residual solvent

Meets the requirements

U hogaansama

Water

≤0.75%

0.40%

Sulphated ash

≤0.1%

0.05%

Assay Ethylene diamine   Theophylline

13.5-15.0%       84.0-87.4%

13.3%           86.7%

 

Aqoonta alaabta:

 

Function:

Aminophylline can be used as dicuretic and the medicine helping to relax the smooth muscle .The aminophylline can relax the bronchus and the smooth muscle of the blood vessel,inhibit the kidney tubules to reabsorb the sodium and the water and enhance the extraction of heart oedema and so on .It is usually used as mono-medicine.It is mainly used in medicine field.

 Application:

Mainly used for asthma, bronchial asthma and chronic bronchitis can also be used for acute heart failure, cardiac asthma, and biliary colic, etc.
Aminophylline is a drug combination consisting of bronchodilator theophylline and ethylenediamine in 2: 1 ratio. It is a kind of non-selective adenosine receptor blocker, histone deacetylase activator and phosphodiesterase inhibition. It is mainly indicated for the treatment of various kinds of lung diseases including asthma, COPD, chronic bronchitis and emphysema. Aminophylline exerts its effect through the component of theophylline in vivo. Theophylline can relax the smooth muscle of the bronchial airways and pulmonary blood vessels. It can competitively inhibits type III and type IV phosphodiesterase (PDE), which breaks down cyclic AMP in smooth muscle cells, possibly leading to bronchodilation. Theophylline also binds to the adenosine A2B receptor to block the adenosine mediated bronchoconstriction. Furthermore, during the inflammatory states, theophylline can activate the histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones to initiate the transcription.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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