Flunixin Meglumine is a kind of veterinary anti-inflammatory analgesic.It has antipyretic,anti-inflammatory and analgesic effects.Alone or in combination with antibiotics can significantly improve clinical symptoms and can enhance the activity of antibiotics. Veterinarians are commonly used clinically to relieve the pain and inflammation caused by visceral angina, muscular and skeletal disorders in horses; control of acute inflammation caused by various diseases of cattle such as laminitis, arthritis, etc. In addition, Swine mastitis, metritis and milk-free syndrome adjuvant therapy.
Flunixin Meglumine is a specific analgesic, antipyretic and anti-inflammatory drug. It is an effective nonnarcotic and non-steroidal anodyne and mainly used for inflammation and ache(stenocardia) of large animals which caused by muscle abnormality,and cures for respiratory disease and eyes surgery of horses etc. Meanwhile, it also can coordinate with other antibiotic drugs to cure for the diseases that caused by endotoxin of cattle and fowl. The product is mainly made for injection, used for animal body.
(1) When used in conjunction with other nsaids, the adverse effects on the gastrointestinal tract can be exacerbated, such as Ulcer, bleeding
(2) Because of the high binding rate of plasma protein, when combined with other drugs, flunisine meglumine may replace other drugs combined with plasma protein or be itself replaced by other drugs, so that the effect of the drug to be replaced is enhanced, or even produce toxicity
Action and use: Antipyretic and analgesic anti-inflammatory drug, one dose, each 1kg bodyweight dog, cat 40mg., 1-2 times a day, Continuous use does not exceed 5 days
Adverse reaction : Long-term use of this product in large doses may lead to gastric ulcer and renal function injury in anima
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Items | Standards | Results | |
Chitarisiko | White or off-white solid powder | Zvinoenderana | |
Identification | By IR | Zvinoenderana | |
By HPLC | Zvinoenderana | ||
Solubility | Soluble in DMF, sparingly soluble in THF, slightly soluble in methanol and acetonitrile, very sightly soluble in ethanol and dichloromethane, insoluble in water | Zvinoenderana | |
Polymorphic Form | Polymorphic form 1 | Zvinoenderana | |
Melting Point | 211ºC~216ºC | 212.8ºC~214.9ºC | |
Water Content | ≤ 0.50% | 0.10% | |
Heavy Metals | ≤ 20ppm | Zvinoenderana | |
Residue on Ignition | ≤ 0.20% | 0.09% | |
Related Substance | Any single impurity: ≤0.10% | 0.06% | |
Total Impurities: ≤1.00% | 0.16% | ||
Assay (on the anhydrous basis) | 98.0%~102.0% | 99.94% | |
Particle Size | D90: ≤100µm | Zvinoenderana | |
Reference Standard | In-house Standard | ||
Mhedziso | The product complied to In-house standard. |
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