Atosiba

Atosiba is indicated for pregnant women over 18 years of age, 24 to 33 weeks of gestation, with normal fetal heart rate, to delay imminent preterm birth when regular contractions are more than 4 times every 30 minutes, each lasting at least 30 seconds, accompanied by cervical dilation of 1 to 3cm (0 to 3cm in primipara), and cervical disappearance of more than 50%.

Atosiban, a nine peptide, is a desamino-oxytocin analogue and a competitive vasopressin/oxytocin receptor antagonist that inhibits the oxytocin-mediated release of inositol triphosphate from the uterine myomembrane.

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