Thiosalicylic Acid

Thiosalicylic acid can be used as trapping agent in the desulfenylation of 3-indolyl sulfides and used to condense with diamines to form macrocyclic diamides. Mainly used in pesticides, dyes, rubber industries, and also used in pharmaceutical products such as methyl salicylate, or used for anti-corrosion treatment of ferrous metals in electroplating industry, also used as metal surface treatment agent, and used as colorant in ceramic industry.

Thiosalicylic acid can be prepared from anthranilic acid via diazotization followed by the addition of sodium sulfide and then reduction with zinc.

Thiosalicylic acid is a precursor to the dyestuff thioindigo. Thiosalicylic acid is also used to make the vaccine preservative thiomersal.

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