Pregabalin powder

Pregabalin is an analogue of the neurotransmitter gamma-aminobutyric acid (GABA), sold under the trade name Lyrica. In December 2004, the FDA approved Pregabalin for the treatment of diabetic neuralgia and herpes zoster neuralgia. Pregabalin is the first drug approved in the United States and Europe for the treatment of both types of pain.

Pregabalin is used primarily for the treatment of peripheral neuralgia and for adjuvant treatment of localized partial seizures.
Pregabalin has a good therapeutic effect on epilepsy, and various animal epilepsy model studies have shown that pregabalin can significantly prevent seizures, and the dose of its active effect is 3-10 times lower than gabapentin. Pregabalin was found to reduce sensory and motor spinal reflexes in rat clamp toe stimulation, reduce behaviors associated with diabetes, peripheral nerve injury, or chemotherapy in neuropathic animal pain models, and inhibit or reduce pain-related behaviors caused by spinal administered stimuli. Animal studies have found that pregabalin may have advantages in combination with opioids. Pregabalin provides a new option for the clinical treatment of neuropathic pain.

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