Propyl chloroformate is an organic compound. It is a colorless liquid, insoluble in water, but soluble in many organic solvents, such as ethanol and ethers. It has a pungent smell.
Propyl chloroformate is often used in organic synthesis as an acylation reagent for the synthesis of ester compounds. It can react with alcohols or phenols to form corresponding esters. In pharmaceutical, pesticide and other fields, it is also widely used in organic synthesis reaction.
The preparation of propyl chloroformate is usually obtained by the reaction of chlorinated formic acid and malonate. During the reaction, chloroformic acid and malonate were esterified to form propyl chloroformate under the catalysis of base.
It is a harsh chemical that can cause irritation by contact with skin, eyes or inhalation of its vapor. Wear personal protective equipment such as protective gloves, glasses and respirators when operating. Use in a well-ventilated environment and avoid contact with fire sources to prevent fire or explosion accidents. In addition, it should be stored in an airtight container, away from fire sources and oxidants. If a leak occurs, appropriate measures should be taken to clean up and deal with it.
Propyl chloroformate can be used in the synthesis of photosensitizers, polymerization catalysts, fungicides and other products. It can also react with liquid blowing agents of alken-based resins for the preparation of light-colored vinyl foam Chemicalbook. Propyl chloroformate has good miscibility with plastic, the decomposition products are colorless, non-toxic, pollution-free and odorless, and high gas emission can be obtained in the range of 40 ~ 120℃, which has broad application prospects.
Propyl chloroformate is an important intermediate in organic synthesis, which is mainly used in organic synthesis.
1. Used as flotation agent and organic synthesis reagent
2. N-propyl chloroformate is an intermediate of the fungicide downocarb.
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Molecular Formula | C4H7ClO2 |
Molar Mass | 122.55 |
Density | 1.09g/mLat 25°C(lit.) |
Boling Point | 105-106°C(lit.) |
Flash Point | 84°F |
Solubility | benzene: miscible(lit.) |
Vapor Presure | 0.87 psi ( 20 °C) |
Appearance | Oil |
Specific Gravity | 1.09 |
Color | Colourless |
Merck | 13,7940 |
Storage Condition | 2-8°C |
Stability | Volatile |
Refractive Index | n20/D 1.404(lit.) |
Physical and Chemical Properties | Trait liquid. boiling point 94 ℃ relative density 1.139 solubility is miscible with benzene and ether. |
Use | Used as flotation agent and organic synthesis reagent |
Propyl chloroformate is an organic compound. It is a colorless liquid, insoluble in water, but soluble in many organic solvents, such as ethanol and ethers. It has a pungent smell.Propyl chloroformate is often used in organic synthesis as an acylation reagent for the synthesis of ester compounds. It can react with alcohols or phenols to form corresponding esters. In pharmaceutical, pesticide and other fields, it is also widely used in organic synthesis reaction.
Propyl chloroformate can be used in the synthesis of photosensitizers, polymerization catalysts, fungicides and other products. It can also react with liquid blowing agents of alken-based resins for the preparation of light-colored vinyl foam Chemicalbook.
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