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How to make "flufenicol + doxycycline" effect enhancement?
The combination of "flufenicol + doxycycline" is a classic combination that everyone is very familiar with. More than ten years ago, the disease was relatively simple, and when the pathogens that were more sensitive to drugs were encountered, the use of this compatibility for treatment could receive better therapeutic effects. However, in recent years, the mixed infection of diseases is more complex or many pathogens are less sensitive to a single drug, and flufenicol and doxycycline are antibacterial drugs, and then use this classic combination, do you feel that the effect is not so obvious? Well, for this combination to work out. First of all, flufenicol and doxycycline should be sufficient. Another is to combine them with other drugs to increase their antibacterial activity. What drugs can be used? 1. For example, in order to improve their antibacterial and anti-mycoplasma activity, colistin sulfate can be added on the basis of flufenicol combined with doxycycline. It will also reduce the amount of flufenicol, doxycycline. 2. In addition to colistin sulfate, the combination of flufenicol and doxycycline can also be combined with compound sulfamethoxide in the treatment of chicken respiratory diseases. Compound sulfamethoxine is a preparation of "compound sulfamethoxine sodium soluble powder", which is made of sulfamethoxine sodium and trimethoprim in accordance with the 5:1 ratio.
The combination of high water soluble flufenicol and compound sulfanilamide sodium soluble powder resulted in the synergistic action of sulfanilamide in the compound sulfanilamide sodium soluble powder. The completely different antibacterial action mechanism and different action peak period on bacteria enabled them to cooperate with each other, enhance each other and greatly expand the range of action on the pathogen spectrum. Coupled with the synergist "trimethoprim" in the compound sulfamethoxine sodium soluble powder, it not only has a significant synergistic effect on sulfamethoxine sodium, it also has a very good synergistic effect on flufenicol!