Orlistat is used with an individualized low-calorie, low-fat diet and exercise program to help people lose weight. Orlistat is used in overweight people who may also have high blood pressure, diabetes, high cholesterol, or heart disease. Orlistat is also used after weight-loss to help people keep from gaining back that weight. Orlistat is in a class of medications called lipase inhibitors. It works by preventing some of the fat in foods eaten from being absorbed in the intestines. This unabsorbed fat is then removed from the body in the stool.
Orlistat blocks some of the fat that you eat, keeping it from being absorbed by your body.
Orlistat is used to aid in weight loss, or to help reduce the risk of regaining weight already lost. This medicine must be used together with a reduced-calorie diet and increased physical activity. Orlistat is for use only in adults that are overweight or obese.
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Product | Orlistat | |
batch No. | 202403001 | |
Mfg. date | 20240315 | |
CAS No. | 96829-58-2 | |
Tests | Specifications | Results |
Description | Appearance: white or almost white crystalline powder | White crystalline powder |
Melting point | 42 46°C | 44 45°C |
Identification | HPLC: the retention time of principal peak should comply with its RS. | Conforms |
IR spectrum should, comply with that of its RS. | Conforms | |
Specific rotation | -48° ~-51°. | -50° |
Related substance | Any other Single impurity NMT 1.0% | 0.18% |
Total impurities NMT 2.0% | 0.95% | |
Residual solvents | NMT 3000ppm | Undetectable |
2000ppm | ||
Water | NMT 0.5% | 0.01% |
Residue on ignition | NMT 0.1% | 0.02% |
Heavy metals | NMT 20ppm | Conforms |
Assay | NLT 98.0% (on the anhydrous basis) | 98.9% |
Conclusion: Conforms to the requirements of in house standard. |
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