Pyrrole

Pyrrole is a five-membered heterocyclic compound containing one nitrogen heteratom, colorless liquid at room temperature, naturally occurring in coal tar and bone oil, rapidly darkening in the air, with a significant irritating odor. The relative density is 0.9691, the boiling point is 130 ~ 131℃, and the freezing point is -24℃. Almost insoluble in water and dilute alkali solutions, soluble in ethanol, ether, benzene and inorganic acid solutions. Chemicalbook is very stable to bases and easily polymerizes into dark red trimer resins in the presence of a small amount of inorganic acids, which will also resinize when stored in light or exposed to air. Pyrrole vapor can show red color when dipped in hydrochloric acid, which is called the pineflakesreaction; pinesplinttest) can be used to identify pyrrole.

Many derivatives of pyrrole are important drugs and substances with strong physiological activity, such as chlorophyll, heme, etc. Pyrrole is the basic structural unit of heme, chlorophyll, bile pigment, some amino acids, some alkaloids and some enzymes. These compounds have strong physiological activities and drug functions. Drugs such as vitamin B12, gastric changanine, hyalinic acid (roundworm repellant) and Lincomycin (antibiotic) all contain hydropyrrole ring structures.

1. For the synthesis of fine chemicals such as pharmaceuticals and fragrances
2. Its derivatives are widely used as raw materials for organic synthesis, medicine, pesticides, spices, rubber vulcanization accelerator, epoxy resin curing agent, etc
3. Used as a standard material for chromatographic analysis, and also used in organic synthesis and pharmaceutical industry
4. Spices. It is mainly used to prepare fruit type and spice flavor
5. Used as an intermediate for the synthesis of medicine and spices.
6. Test gold selenite and silicic acid. Determination of chromate, gold, iodate, mercury, selenite, silicon and vanadium.

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