Xanthan Gum A Comprehensive Review from PubMed Perspective Xanthan gum, a polysaccharide derived from the fermentation of the bacterium Xanthomonas campestris, has gained significant attention in various industries, particularly in food, pharmaceuticals, and cosmetics, due to its unique rheological properties. A thorough exploration of the PubMed database reveals a wealth of research on this versatile substance. PubMed, a comprehensive repository of biomedical literature, houses numerous studies that delve into the diverse applications and mechanisms of xanthan gum. Its use as a food additive, for instance, is well-documented. It functions as a stabilizer, thickener, and emulsifier, enhancing texture and mouthfeel in a wide range of products from salad dressings to ice cream. Studies have shown that xanthan gum can improve the nutritional profile of gluten-free foods by increasing their viscoelastic properties, making them more similar to their gluten-containing counterparts. In the pharmaceutical sector, xanthan gum has found its niche as a binder, disintegrant, and controlled-release agent in tablet formulations. PubMed research highlights its ability to modify drug release kinetics, potentially improving patient compliance and therapeutic outcomes. Additionally, it has been investigated for its potential role in drug delivery systems, particularly for targeted and sustained drug release. The cosmetic industry also benefits from xanthan gum's properties, using it as a natural alternative to synthetic thickeners. PubMed articles report its efficacy in creating smooth, stable skincare products and in hair care, where it improves manageability and reduces frizz PubMed articles report its efficacy in creating smooth, stable skincare products and in hair care, where it improves manageability and reduces frizz PubMed articles report its efficacy in creating smooth, stable skincare products and in hair care, where it improves manageability and reduces frizz PubMed articles report its efficacy in creating smooth, stable skincare products and in hair care, where it improves manageability and reduces frizzxanthan gum pubmed. Beyond these conventional uses, xanthan gum has been explored for its potential health benefits. Some PubMed studies suggest it may have prebiotic effects, promoting the growth of beneficial gut bacteria. Other research explores its possible role in controlling blood sugar levels and managing obesity, although more extensive clinical trials are needed to substantiate these claims. Furthermore, xanthan gum's environmental impact and biodegradability have been topics of interest. Studies have examined its potential use in eco-friendly drilling fluids and as a bio-based alternative to petrochemical-based polymers. In conclusion, the PubMed database provides a rich source of information on xanthan gum, illustrating its multifaceted roles across various industries. While its primary applications are well-established, ongoing research continues to uncover new possibilities and deepen our understanding of this remarkable biopolymer. Future studies are expected to further explore its potential in areas such as personalized medicine, sustainable materials, and functional foods.