Naproxen is an organic compound with the chemical formula C14H14O3. Naproxen is a non-steroidal anti-inflammatory drug with anti-inflammatory, antipyretic and analgesic effects. It is a PG synthetase inhibitor with similar efficacy to aspirin in rheumatoid arthritis and osteoarthritis. This product can obtain satisfactory results, while the inhibitory effect of platelets is small.
White or white crystalline powder, odorless, slightly bitter, soluble in water.
Non-steroidal anti-inflammatory drugs, also have analgesic and antipyretic effects. It is mainly used for the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout, chronic degenerative diseases of the motor system (such as joints, muscles and tendons) and mild and moderate pain, such as dysmenorrhea.
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Hebei Disha Import and Export Trade Co., Ltd.
Certificate of Analysis
Product |
Naproxen |
Batch No. |
20240518 |
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Packing |
25kg/Carton |
Certificate No |
DS20240521 |
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Specification |
USP 37 |
Analysis Date |
MAY.21, 2024 |
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Batch Qty. |
3000kg |
Reporting Date |
MAY.21, 2024 |
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MFG Date |
MAY.18, 2024 |
Expiry Date |
MAY.17, 2026 |
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ITEM |
SPECIFICATION |
RESULT |
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Packaging and storage |
Preserve in tight containers, protected from light |
Conforms |
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Description |
White to off-white, practically odorless, crystalline powder |
Conforms |
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Identification |
A: Infrared Absorption |
Conforms |
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B: Ultraviolet Absorption |
Conforms |
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Loss on drying |
≤0.5% |
0.02% |
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Specific rotation |
+83.0 °~+89.5° |
+87. 1 ° |
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Heavy metals |
≤0.002% |
<0.002% |
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Residual Solvent |
Methanol |
≤50ppm |
<38ppm |
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Toluene |
≤45ppm |
<1ppm |
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Chromatographic purity |
Single impurity ≤0.5% |
<0.5% |
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Total impurities ≤2.0% |
<2.0% |
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Assay |
98.5%~101.5% |
99.7% |
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Conclusion: Up to the standard of USP37. |
The common adverse effects of naproxen include gastrointestinal ulcers, bleeding, kidney damage, etc., and may also increase the risk of cardiovascular disease and stroke. Contraindications for naproxen include allergy to the drug or other NSAIDs, active gastrointestinal ulcers, severe liver insufficiency, severe renal insufficiency, severe heart failure, and late pregnancy.
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