Metoclopramide is a chemical substance with a molecular formula of C14H22ClN3O2 and a molecular weight of 299.80. The application of metronidazole during and after abdominal surgery can prevent visceral traction reactions, reduce nausea, vomiting, abdominal distension, intestinal adhesions and other complications. It can also be used to treat renal colic, prevent cesarean section complications, and promote lactation. It has good curative effect in the treatment of migraine and severe urinary retention caused by diabetic neurogenic bladder.
Metoclopramide is a medicine indicated for stomach and esophageal problems. This product is mainly used to treat nausea and vomiting, and to assist patients with gastric emptying disorders to empty the stomach and treat gastroesophageal reflux. This product can also be used to treat migraine and to treat gastroparesis. Common side effects include fatigue and diarrhea. More serious side effects include depression and some movement disturbances, including tardive dyskinesia, which is also known as antipsychotic malignant syndrome. It is not recommended to take this product for more than 12 weeks. This product belongs to the category B drug of pregnancy classification in the United States, and it is a category A drug in Australia, which means that there is no evidence that the drug will cause harm during pregnancy. This product is a dopamine receptor antagonist.
The application of metronidazole during and after abdominal surgery can prevent visceral traction reactions, reduce nausea, vomiting, abdominal distension, intestinal adhesions and other complications. It can also be used to treat renal colic, prevent cesarean section complications, and promote lactation. It has good curative effect in the treatment of migraine and severe urinary retention caused by diabetic neurogenic bladder.
1.It can be used for vomiting caused by lung tumor surgery, tumor radiotherapy and chemotherapy, sequelae of brain trauma, acute craniocerebral injury and drugs.
2. It also has a good effect on gastric distension dyspepsia, loss of appetite, belching, nausea and vomiting.
3, can be used for sea and air operations caused by vomiting and motion sickness.
4, can increase esophageal sphincter pressure, thereby reducing the incidence of gastrointestinal reflux induced aspiration pneumonia during general anesthesia; It can reduce the nausea and vomiting reaction during barium meal examination and promote the passage of barium. Take before duodenal intubation to facilitate smooth intubation.
5. It has certain curative effect on diabetic gastroparesis and gastroptosis; It can also be used for pyloric obstruction and duodenal ulcers that do not respond to conventional treatment.
6, can reduce the nausea caused by migraine.
7, the prolactin effect of this product can be tried in women with serious milk shortage.
8, can be used for the auxiliary treatment of biliary tract diseases and chronic membrane adenitis.
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ITEMS OF ANALYSIS | SPECIFICATIONS | RESULT | |||||||
Appearance | Off-white EU/mgle yellow crystallinepowder | Off-white crystalline powder | |||||||
Solubility | Meets the requirements | Meets the requirements | |||||||
Identification | A. Infrared spectium should conform | Complies | |||||||
B. Should conform | Complies | ||||||||
Specific rotation | +58°~64° | +61° | |||||||
Loss on drying | ≤3.0% | 2.30% | |||||||
PH | 4.5~6.5 | 5 | |||||||
Moisture(water) content | ≤6.0% | <4.6% | |||||||
Absorbance | ≤0.20% | Commplies | |||||||
Absorbance index | 360-390 | Commplies | |||||||
Assay of Cefotaxime (calculated on the dried basis) |
≥95% | 99% | |||||||
Any individual impurity | ≤1.0% | 0.38% | |||||||
Sum of all impurities | ≤3.0% | 1.40% | |||||||
Bacterial endotoxins | ≤0.20 USP EU/mg | <0 20 USP EU/mg | |||||||
Sterility | Meets the requirements | Meets the requirements |
Metoclopramide is a chemical substance with a molecular formula of C14H22ClN3O2 and a molecular weight of 299.80. The application of metronidazole during and after abdominal surgery can prevent visceral traction reactions, reduce nausea, vomiting, abdominal distension, intestinal adhesions and other complications. It can also be used to treat renal colic, prevent cesarean section complications, and promote lactation. It has good curative effect in the treatment of migraine and severe urinary retention caused by diabetic neurogenic bladder.
Metropol is a dopamine D2 receptor blocker, which can block the D2 receptors in the brain chemoemetic zone (CTZ) and produce a powerful central antiemetic effect. It is often used clinically to treat vomiting caused by various reasons and has a good therapeutic effect.
Metoclopramide is a treatment of choice of post-operative nausea and vomiting (PONV) prophylaxi
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