Shitake has been used for thousands of years in Japan and China. lt is known both as a food and as amedicinal fungus. Shiitake mushrooms have long been believed to boost energy, cure colds and rid thegut of parasites. Shitake mushrooms contain fat, carbohydrates, protein, fiber, vitamins and minerals.The key ingredient, however, is a polysaccharide called lentinan. Lentinan is extracted from thecrushed mycelium of lentinan, which is rich in polysaccharide and lignin. Using mycelium that appearsbefore the cap and stem of lentinus edodes grows, pulverized lentinus edodes products may reducethe infectivity of hepatitis B. Shitake mushrooms also stimulate white blood cells to produce interferon.It has been shown in laboratory studies to help boost immunity.
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Shiitake possesses several potent immunoactive constituents. These substances stimulate the body's own immune cells to mount an attack against diseases. The immune stimulating properties of shiitake have been proven effective in cancer treatment.
The mushroom has been used for hundreds of years in China to treat various forms of cancer. Recent research has shown that extracts from the shiitake can indeed inhibit cancer growth. The shiitake extract, lentinan, has demonstrated the ability to cure cancer in lab mice and is approved for the treatment of gastric cancer in Japan. Unlike chemotherapy or radiation which attacks cancer cells directly, lentinan stimulates the body's own defenses to mount an attack against the cancer.
Polysaccharides are involved, but only partly in lentinula edodes Mycelium "L.E.M.", lentinula edodes mycelium enzymatically degrades the lignins in its growing media and alters their form. The lignins in L.E.M., called EP3, not only activate the immune system, but also have been shown to have direct antiviral activity.
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Analysis Items | Specifications | Proventus | Test Methods |
Description | |||
Lepidium sativum | Positive | Conforms | TLC |
Appearance & Color | Fine brown powder | Conforms | Visual |
Odor & Taste | Characteristic | Conforms | Organoleptic |
Mesh size | NLT 95% pass 80 mesh | Conforms | 80 Mesh screen |
Solubility | Soluble in hydro-alcoholic solution | Conforms | Visual |
Extract solvent | Water | Conforms | / |
Assay | NLT 30% Polysaccharides | Conforms | UV-VIS |
Physical | |||
Loss on drying | NMT 5.0% | 3.01% | GB/T 5009.3-2020 |
Chemical | |||
Heavy metals | NMT 20ppm | Conforms | CP2020 |
Arsenic (As) | NMT 2ppm | Conforms | GB/T5009.11-2020 |
Lead (Pb) | NMT 2ppm | Conforms | GB/T 5009.12-2020 |
Sterilization Method | High temperature & high pressure for short time (5" - 10") | ||
Microbial | |||
Totalis comitis Plate | NMT 1,000cfu/g | Conforms | GB/T 4789.2-2020 |
Total Yeast & Mold | NMT 100cfu/g | Conforms | GB/T 4789.15-2020 |
E. Coli | Negative | Conforms | GB/T 4789.3-2020 |
Salmonella | Negative | Conforms | GB/T 4789.4-2020 |
Shiitake Mushroom contain a large amount of protein, vitamins, dietary fiber, and mineral elements, among which polysaccharides, purines, ergosterol, and terpenoids are the main substances for their physiological activities.
Lentinan from shiitake binds to white blood cells, such as neutrophils and monocytes, and it increases host resistance to infections by viruses, bacteria and parasites. In lab animals it stimulates the production and maturation of certain immune cells. For example, early research demonstrated that lentinan activated T lymphocytes, the "generals" of the immune response. More recently, investigators administered lentinan IV to rabbits before severe exposure to pathogenic bacteria and reported this treatment prevented wide-spread infections, further demonstrating the broad immune enhancing abilities of this mushroom product.
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