Ketoconazole is a synthetic antifungal drug used primarily to treat fungal infections. Ketoconazole is sold commercially as a tablet for oral administration (although this use has been discontinued in a number of countries), and in a variety of formulations for topical administration, such as creams (used to treat tinea; cutaneous candidiasis, including candidal paronychia; and pityriasis versicolor) and shampoos (used primarily to treat dandruff-seborrhoeic dermatitis of the scalp).
Ketoconazole is used to treat certain serious fungal infections in the body. Ketoconazole belongs to the class of drugs called antifungals. It works by stopping the growth of the fungus.
Ketoconazole is a kind of imidazoles broad-spectrum antifungal drug, marketed under the trade names of Jindaknin and kochin. It inhibits the biosynthesis of ergosterols on fungal cell membranes by highly selective interference with the cytochrome P-450 activity of fungi Deep fungal infection is effective, not only can inhibit the growth of fungi, but also can inhibit spores into mycelium, prevent further infection low concentration bacteriostasis, high concentration bacteriostasis on Candida pigmentum fungi, spheroidia, histoplasmosis, sporotrichia and trichotrichia trichotrichia have antibacterial effects, clinical application for the treatment of tinea pedis hand, tinea pedis skin, tinea body, tinea jock Thrush spotted tinea and candidiasis of the skin.
1.Ketoconazole is usually prescribed for fungal infections of the skin and mucous membranes, such as athlete's foot, ringworm, candidiasis (yeast infection or thrush), jock itch, and tinea versicolor.
2.Topical ketoconazole is also used as a treatment for dandruff (seborrheic dermatitis of the scalp) and for seborrheic dermatitis on other areas of the body, perhaps acting in these conditions by suppressing levels of the fungus Malassezia furfur on the skin.
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Items
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仕様
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結果
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外観
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White Powder
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準拠
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Purity(HPLC)
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≥99%
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99.6%
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Water content(KF)
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≤5%
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2.2%
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Heavy metal content(AAS)
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||
鉛
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≤0.5ppm
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準拠
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として
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≤0.5 ppm
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準拠
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Hg
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≤0.5 ppm
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準拠
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Cd
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≤0.5 ppm
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準拠
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Total microbial count(GB4789.2)
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≤750CFU/g
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N.D
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Coliform(GB4789.3)
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<3MPN/g
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N.D
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Ethanol(By GC)
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≤2%
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0.012%
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Escherichia coli.
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ネガティブ
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準拠
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サルモネラ
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ネガティブ
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準拠
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Ketoconazole is usually prescribed for fungal infections of the skin and mucous membranes, such as athlete's foot, ringworm, candidiasis (yeast infection or thrush), jock itch, and tinea versicolor.
Ketoconazole is an antifungal drug used to treat athlete's foot and excessive dandruff.
Pharmacology Ketoconazole is a pyrrole antifungal drug, which has antibacterial effects on deep infection fungi such as Candida, Color fungus, Coccidioides, Histoplasma, Sporothrix, etc., and has antibacterial effects on hair. Ringworm, etc. also have antibacterial activity.
Ketoconazole is indicated for the treatment of the following systemic fungal infections:
1. Candidiasis, chronic mucocutaneous candidiasis, oral candidiasis, urinary tract candidiasis, chronic and recurrent vaginal candidiasis that are ineffective with local treatment.
2. Dermatitis blastomycosis.
3. Coccidioidomycosis.
4. Group Chemicalbook Histoplasmosis.
5. Pigmentation fungal disease.
6. Paracoccidioidomycosis.
For dermatomycosis, tinea versicolor and tinea versicolor caused by dermatophytes and yeasts, this product can be used when topical treatment or oral griseofulvin is ineffective, or when severe and refractory skin fungal infections are difficult to accept griseofulvin treatment. treat.
製品カテゴリー