Retinoic Acid Powder is yellow crystalline powder. Retinoic Acid Powder easily dissolved in chloro and dissolved in carbinol, ethanol and retinoic acid also dissolved in vegetable oil and lipid. Retinoic Acid Powder instability exposed in light and caloricr, easily absorbing moisture and metamorphosed in water. Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel It is also used to treat acute promyelocytic leukemia. It is also available as a generic.Retinoic acid is a metabolite of vitamin A (retinol) that mediates the functions of vitamin A required for growth and development. Retinoic acid is required in chordate animals, which includes all higher animals from fish to humans. During early embryonic development, retinoic acid generated in a specific region of the embryo helps determine position along the embryonic anterior/posterior axis by serving as an intercellular signaling molecule that guides development of the posterior portion of the
embryo. It acts through Hox genes, which ultimately control anterior/posterior patterning in early developmental stages. The key role of retinoic acid in embryonic development mediates the high teratogenicity of retinoid pharmaceuticals, such as isotre tinoin used for treatment of cancer and acne. Oral megadoses of pre-formed vitamin A (retinyl palmitate), and retinoic acid itself, also have teratogenic potential by this same mechanism.
Retinol can effectively prevent obesity, keep women slim figure.
Retinol is used to promote bone growth, help teeth growth, regeneration.
Retinol can adjust the skin and cuticle metabolic effect, can be anti-aging, and to wrinkles.
Retinol can help protect skin, mucous membrane from bacteria violations, healthy skin, prevent skin cancer.
Retinol also can prevent nyctalopia, eyesight decline, the treatment of various eye disease, make the woman good eyes.
Retinol can reduce sebaceous overflow and make the skin elasticity, and at the same time, desalination spot, smooth skin.
1.Prevent night blindness and vision loss; it's helpful to the treatment of eye diseases. (VA could promote the formation of photo pigment inside eyes)
2.Anti-respiratory-infection
3.Immune-system enhancing
4.Promote early recovery.
5.Keep healthy of organizations or organ surface. 6,Remove senile plaques
7.Promote healthy growth, strong muscularity, protect skin, hair, teeth and teeth gums.
8.The external use is helpful to the treatment of acne, pimple, skin surface ulcerations.
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ITEM | SPECIFICHE | RESULT | METHOD |
Aspetto | Yellow powder, neutral odor, highly hygroscopic | Conforme | Visual |
Identificazione | Standard solution and test solution same spot,RF | Conforme | TLC |
Specific Optical | -2.4°~ -2.8° | -2.72° | |
Heavy metals (as PB) | ≤10ppm | Conforme | AAS |
Sulfate (SO4) | ≤0.02% | Conforme | Colorimetry |
Chloride (Cl) | ≤0.02% | Conforme | Colorimetry |
Phosphate Ion (P) | ≤5ppm | Conforme | Colorimetry |
Residual solvent(ethanol) | ≤1,0% | Conforme | HS-GC |
pH | 4.5~7.0 | 5.10 | |
Related substance | Spot not bigger than standard solution spot | No spot | TLC |
Water Content | ≤2% | 0.26% | KF |
Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
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