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(propylene glycol c3h8o2 characteristics and applications)
Propylene glycol (C₃H₈O₂) represents a pivotal industrial compound with the molecular formula CH₃CHOHCH₂OH. This synthetic organic alcohol belongs to the diol family, featuring two hydroxyl groups that determine its reactive behavior. Originally developed in the 1920s, annual production now exceeds 2.3 million metric tons globally to meet diverse industrial demands. Its GRAS (Generally Recognized As Safe) designation by the FDA enables pharmaceutical and food applications where alternatives prove unsuitable. The compound exists in two enantiomeric forms, though industrial production typically yields the racemic mixture unless specified otherwise.
Key characteristics define propylene glycol's utility. With a density of 1.036 g/cm³ at 20°C and freezing point of -59°C, it remains liquid across extreme temperatures. The hygroscopic nature allows absorption exceeding 45% moisture by weight at 60% relative humidity. Chemically, it exhibits amphiphilic behavior with a log P value of -1.69, enabling dissolution of both hydrophilic and hydrophobic compounds. Thermal decomposition initiates at 188°C under atmospheric conditions, while surface tension measurements show 38.8 mN/m at 25°C.
Reactivity centers on hydroxyl groups, permitting esterification and etherification reactions critical for polymer production. The compound resists oxidation under standard conditions but reacts vigorously with strong oxidizing agents. Flash point measurements range between 99-107°C depending on concentration, classifying it as combustible rather than flammable.
Propylene glycol outperforms alternatives like ethylene glycol through lower mammalian toxicity (LD50 oral rat: 20 g/kg) and superior biocompatibility. Environmental persistence measurements show 88% biodegradation within 28 days (OECD 301D), while bioconcentration potential remains negligible (BCF: 0.2-0.3). As heat transfer fluid, its volumetric heat capacity reaches 3.43 J/cm³K versus 1.88 J/cm³K for mineral oil.
Technical highlights include:
Manufacturer | Purity Grade (%) | Color (APHA) | Heavy Metal Limit (ppm) | Specialized Grades |
---|---|---|---|---|
Dow Chemical | 99.8 | 10 max | 1.0 | USP, EP, Bio-based |
BASF | 99.7 | 15 max | 2.0 | Pharma, Food |
LyondellBasell | 99.5 | 20 max | 5.0 | Industrial, Tech |
ADM | 99.9 | 5 max | 0.5 | USP, Kosher, Halal |
Formulators tailor propylene glycol properties through blending and chemical modification. Aircraft deicing fluids combine C₃H₈O₂ with thickening agents to achieve viscosity profiles between 18-35 cSt at -40°C. Pharmaceutical solutions enhance solubility via eutectic mixtures, with common ratios including:
Recent developments include polymer-bound PG derivatives exhibiting 60% reduced absorption rates for sustained-release applications, and renewable variants derived from glycerol with ≥99.3% equivalency to petroleum-sourced material.
Pharmaceuticals: Oral solutions employ PG concentrations averaging 22% (v/v) to solubilize hydrophobic APIs. Market analysis confirms 78% of pediatric syrups contain PG versus 41% using alcohol bases.
Aerospace: Deicing formulations utilize 50% PG solutions achieving -51°C freezing point depression. Testing confirms removal of 98.3% ice accumulation in 8 minutes at -25°C on wing surfaces.
Food Processing:
Industrial applications demonstrate increased viscosity index lubricants containing 12% PG exhibit 15% longer service intervals than glycol-free alternatives.
Research focuses on enhancing PG's sustainability profile through bio-based production, with recent advances achieving 92% yield from renewable feedstocks. Novel dimerization techniques produce propylene glycol diesters exhibiting 40% lower volatility while maintaining solvation capacity. Industry forecasts predict 4.9% CAGR through 2028, driven by pharmaceutical applications and HVAC system demand.
Ongoing investigations explore nanoemulsion systems where C₃H₈O₂ stabilizes particle suspensions below 100nm diameter. Regulatory developments increasingly favor PG over ethylene glycol, with 14 countries adopting stricter limitations on EG in consumer products since 2021. These evolving standards will likely expand propylene glycol's role in emerging sectors including biodegradable polymers and next-generation battery cooling systems.
(propylene glycol c3h8o2 characteristics and applications)
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