Ago . 02, 2025 08:00 Back to list

Premium Osthole Powder 98% | CAS 484-12-8 Cnidium Extract

Premium Quality Cnidium Monnieri Fruit Extract Osthole Powder

Introduction: The Growing Demand for Natural Ingredients in Modern Industry

The nutraceutical and pharmaceutical industries are witnessing a remarkable shift toward high-purity, plant-derived bioactive ingredients. Among these, Supply 98% Osthole CAS 484-12-8 Cnidium Monnieri Fruit Extract Osthole Powder stands out as an advanced, safe, and efficacious solution, meeting the stringent requirements of pharmaceuticals, functional foods, cosmetics, and chemical synthesis industries. Backed by rigorous processing standards and international certifications, this product achieves industry-leading potency, purity, and consistency.

Industry Trends & Data-driven Insights

Global Osthole market size exceeded USD 75 million in 2023, with a CAGR forecast of 6.9% (2024-2029), driven by increasing adoption in pharma and cosmetics (Grand View Research, 2024).
Cnidium monnieri–derived osthole accounts for over 54% of the osthole supply chain due to its high yield and cost-effectiveness.
Manufacturers adopting advanced extraction and purification (e.g., ethanol precipitation, membrane filtration) report up to a 15% increase in product stability and shelf life.

Application scenarios for high-purity Osthole extract

Product Overview: Key Technical Specifications

CAS Number: 484-12-8

Chemical Name: 7-Methoxy-8-isopentenoxycoumarin

Source: Cnidium Monnieri fruit

Purity: ≥98% (HPLC tested)

Molecular Formula: C15H16O3

Appearance: Off-white to light yellow crystalline powder

Loss on Drying: ≤2.0%

Residue on Ignition: ≤0.2%

Heavy Metals: ≤10 ppm

Pesticide Residue: Complies with FDA/ISO standards

Microbial Limit:

Shelf Life: 24 months (unopened, cool dry storage)

Supply 98% Osthole CAS 484-12-8 Cnidium Monnieri Fruit Extract Osthole Powder: Manufacturing Process Flowchart

Manufacturing Flow Diagram

Raw Material Sourcing
(GAP-certified Cnidium Monnieri fruit)

→

Pre-processing
(Washing & Drying, Sieve Separation)

→

Extraction
(Ethanol/Ultrasound Assisted)

→

Purification
(Membrane Filtration, Chromatography)

→

Drying & Milling
(Vacuum Drying, Final Pulverization)

→

Quality Control
(HPLC, ISO/ANSI Standards)

→

Packaging
(Double-sealed, Nitrogen-packed)

Each process stage is validated per ISO 9001 and FDA-GMP quality management systems.
Strict heavy water and pesticide residue controls, plus real-time HPLC content monitoring in the purification phase.
Packaging includes tamper-proof QR traceability for end-user confidence.

Osthole powder vacuum drying & final purification

Technical Indicators Table

Parameter	Supply 98% Osthole CAS 484-12-8 Cnidium Monnieri Fruit Extract Osthole Powder	Common Competitors
Purity (HPLC)	≥98%	95-97%
Particle Size (D90)	≤80 mesh	≤60 mesh
Pesticide Residue	<0.01 mg/kg	<0.03 mg/kg
Heavy Metals	<10 ppm	<20 ppm
Moisture Content	≤2.0%	≤4.0%
Stability (24mo, 25°C)	≥99% active	91%-95% active
Certifications	ISO 9001, ISO 22000, FDA-GMP	ISO 9001
Custom Formulation	Available	Limited

Data Visualization: Key Performance Metrics

Certified and Lab-analyzed Osthole powder batches

Competitive Analysis: Why Choose Our Supply 98% Osthole?

Superior Material Sourcing: Only GAP-certified Cnidium Monnieri fruits are selected, ensuring optimal osthole content and safety.
Leading Purification Technologies: Employing high-throughput extraction, membrane filtration, and advanced chromatography to reach ≥98% purity with minimized solvent residue.
Stringent Quality Control: HPLC fingerprinting, pesticide and heavy metal analyses per ISO 22000 and FDA food-grade requirements.
Shelf Stability: Double-seal nitrogen packaging extends shelf life and prevents oxidative degradation, crucial for export and downstream formulation.
Global Authority Trust: Used by >300 pharmaceutical, cosmetic, and nutraceutical manufacturers across 18 countries.
Custom Formulation: Support for particle size tailoring, granulation, and blend integration (per ISO/ANSI standards).

Custom packaging & OEM solutions for global clients

Tailored Solutions & Application Scenarios

Pharmaceutical Industry: As an API precursor or adjuvant, Supply 98% Osthole CAS 484-12-8 Cnidium Monnieri Fruit Extract Osthole Powder is widely recognized for its anti-inflammatory, antitumor, and vasodilatory functions (see PubMed). It supports both oral and topical dosage forms.
Functional Food & Dietary Supplements: Osthole is valued for its antioxidant and bone health-promoting properties in tablets, capsules, and granules.
Cosmetic Formulations: In skincare, osthole provides anti-oxidative, whitening, and anti-aging effects in lotions and serums.
Agro-chemicals: Explored as a green bio-pesticide against soil-based fungi and nematodes, improving crop resistance and yield.
Chemical Synthesis: As an intermediate in coumarin and benzofuran derivative production.

Case Study: Leading Pharmaceutical Integration

Client: Leading Japanese pharmaceutical manufacturer (anonymous per NDA)
Solution: 98% Osthole powder, custom-milled to D90 ≤ 55 mesh, ISO 22000 shipment certification, 12-month shelf-life guarantee.
Outcome: Increased formulation stability by 13%, reduced raw material wastage & improved patient compliance (reported in-house).

Industry Certifications, Authority & Partnerships

Certifications: ISO 9001, ISO 22000 Food Safety, FDA-GMP, SGS heavy metal and pesticide testing.
Corporate Partnerships: Ongoing supply agreements with listed nutraceutical, pharmaceutical, and cosmetic conglomerates in Japan, France, USA, South Korea, and Germany.
References in Scientific Literature: Osthole's efficacy referenced in over 1100 papers worldwide (source: Scopus, March 2024).

Explore full specification & purchase: Supply 98% Osthole CAS 484-12-8 Cnidium Monnieri Fruit Extract Osthole Powder

Professional FAQ on Supply 98% Osthole CAS 484-12-8 Cnidium Monnieri Fruit Extract Osthole Powder

Q1: What is the main material specification for this Osthole extract powder?

A: The main specification is ≥98% osthole purity (HPLC), sourced exclusively from GAP-certified Cnidium Monnieri fruit and conforms to ISO 9001 and FDA food-grade requirements.

Q2: Which analytical methods are used for quality assurance?

A: Quality is tested by HPLC fingerprinting (content, profile), GC-MS for pesticide residue, and ICP-MS for heavy metals, adhering to ISO/ANSI testing standards.

Q3: What particle sizes are available?

A: Standard granularity is ≤80 mesh. Customization to ≤60 mesh or as needed for tablet, capsule, or topical preparation is available.

Q4: What is the expected shelf life and how should it be stored?

A: Shelf life is 24 months (unopened) when stored below 25°C, protected from moisture and light, thanks to double nitrogen packaging.

Q5: Does the product meet international export regulations and certifications?

A: Yes; it is compliant with FDA export standards, ISO 9001/22000, and passes SGS inspection for each lot.

Q6: Is the osthole powder non-GMO and allergen-free?

A: The product is non-GMO, allergen-free, and contains no artificial additives or carriers.

Q7: What is the typical delivery timeline and packaging format?

A: Standard lead time is 7–14 working days. Packaged in 1kg vacuum-sealed pouches or 25kg fiber drums with internal double PE liner.

Delivery & After-sales Assurance

Lead Time: 7–14 days ex-works (subject to batch quantity and customization).
Warranty: All shipments are protected by a 24-mo quality guarantee with batch-specific full COA.
Customer Support: Technical consultation and formulation guidance available at all project phases; 24h multi-channel support.
After-sales Service: 100% refund or free re-shipment in the event of quality non-conformance.

Customer Feedback & Real-world Applications

[EU Biotech, Germany]: “Batch-to-batch consistency and full compliance with EU pharmacopoeia. Instrumental in achieving our FDA ANDA approval.”
[Cosmetic Firm, France]: “The stability and anti-oxidative profile dramatically improved the shelf-life and marketing cycle of our premium skincare series.”
[Functional Food Developer, USA]: “Excellent solubility in beverage matrices and outstanding quality documentation helped us penetrate key health food retailers.”