Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel It is also used to treat acute promyelocytic leukemia. It is also available as a generic.
Its success in treating acute promyelocytic leukemia was a major breakthrough in the treatment of this type of leukemia.It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor gene to the promyelocytic leukemia gene.
This fusion PML-RAR protein is responsible for preventing immature myeloid cells from differentiating into more mature cells. This block in differentiation is thought to cause leukemia.
1. For abnormal acne, ichthyosis and abnormal psoriasis
2. Also known as vitamin , retinoic acid, the metabolic intermediate product of vitamin A in this strain, mainly affects the growth of bone and the metabolism of epithelial cells, and has the effects of promoting epithelial cell proliferation and keratinization. It is suitable for acne vulgaris, lichen planus (including oral lichen planus), leukoplakia, pityriasis red hair and pityriasis simplex on the face, etc. It can also be used as an adjuvant therapy for psoriasis (psoriasis), and can also be used to treat multiple vulgaris and various skin diseases such as ichthyosis and keratosis follicularis.
1. Tretinoin Powder is a drug commonly used to treat acne vulgaris and keratosis pilaris.
2. Tretinoin Powder is available as a cream or gel.
3.Tretinoin Powder is also used to treat acute promyelocytic leukemia.
4. Tretinoin Powder can stimulate skin growth and keep epidermic normal.
5. Tretinoin Powder can slow down skin aging process for solarization, remove tiny wrinkles.
6. Tretinoin Powder can reduce skin roughness, so skin will become ruddy.
Anyị nwere ọtụtụ ụlọ ọrụ dị elu nke nwere nkwado miri emi, nke nwere ike inye gị ngwaahịa dị elu na ọnụ ahịa asọmpi. Anyị nwekwara ike inye ego maka nnukwu ịzụrụ ihe. Anyị na-akwado ọtụtụ ụlọ ọrụ na-ebuga ibu ndị ọkachamara, nwere ike ịnapụta ngwaahịa n'enweghị nsogbu na aka gị. Oge nnyefe bụ ihe dịka ụbọchị 3-20 mgbe nkwenye nke ịkwụ ụgwọ gasịrị.
Items | Nkọwapụta | Nsonaazụ |
Ọdịdị | Yellow to orange crystalline powder | Na-akwado |
njirimara | The infrared absorption is same as referance | Na-akwado |
Should exhibits maximum absorption at 352nm | Na-akwado | |
Limits of isotretinoi | ≤5.0% | 0.41% |
Loss on drying | ≤0.5% | 0.03% |
Heavy metals | ≤0.002% | <0.002% |
Residue on ignition | ≤0.1% | 0.03% |
Assay(on dried basis) | 98.0%~102.0% | 100.5% |
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