Valsartan is used clinical for receptor antagonist of angiotensin AT1, has good effect to the different degree of hypertension patients who used other antihypertensive without efficacy , is a new generation of highly efficient antihypertensive .
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. Overall, valsartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced cardiac activity, and increased excretion of sodium.
Valsartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions. Pharmacological blockade of RAAS via AT1 receptor blockade inhibits negative regulatory feedback within RAAS, which is a contributing factor to the pathogenesis and progression of cardiovascular disease, heart failure, and renal disease. In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling.
Valsartan is an angiotensin II receptor antagonistwith particularly high affinity for the type I (AT1) angiotensin receptor. By blocking the action of angiotensin, valsartan dilates blood vessels and reduces blood pressure. In the U.S., valsartan is indicated for treatment of high blood pressure, congestive heart failure (CHF), or post-myocardial infarction (MI) .
Kami memiliki banyak pabrik berkualitas tinggi dengan kerja sama yang mendalam, yang dapat memberi Anda produk berkualitas tinggi dan harga yang kompetitif. Dan kami juga dapat memberikan diskon untuk pembelian dalam jumlah besar. Dan kami bekerja sama dengan banyak perusahaan ekspedisi profesional, dapat mengirimkan produk dengan aman dan lancar ke tangan Anda. Waktu pengiriman sekitar 3-20 hari setelah konfirmasi pembayaran.
Barang | Test Standard | Testing Result | |
Penampilan | Powder | Sesuai | |
Color | bubuk putih | Sesuai | |
Particle Size | 100% pass 80 mesh | Sesuai | |
Oder | Characteristic | Sesuai | |
Taste | Characteristic | Sesuai | |
Kerugian pada Pengeringan | ≤5.0% | 2.20% | |
Residue on Ignition | ≤0.1% | 0.05% | |
Residual acetone | ≤0.1% | Sesuai | |
Residual Ethanol | ≤0,5% | Sesuai | |
Heave Mentals | ≤10ppm | Sesuai | |
Na | ≤0.1% | <0.1% | |
Pb | ≤3 ppm | Sesuai | |
Jumlah Plat | <1000CFU/g | Sesuai | |
Yeast & Mold | <100 CFU /g | Sesuai | |
E. Coli | Negatif | Sesuai | |
Salmonella | Negatif | Sesuai | |
Conclusion: Conform with USP Standard |
1. Apakah Anda pabrik atau perusahaan dagang?
Kami adalah perusahaan yang mengintegrasikan industri dan perdagangan, menyediakan layanan satu atap. OEM dapat diterima.
2. Apakah Anda menyediakan sampel? Apakah gratis atau ekstra?
Sampel gratis. Biaya pengiriman sampel harus dibayar di sisi Anda.
3. Apakah Anda memiliki sertifikat terkait kendali mutu?
Sertifikasi ISO 9001:2008 untuk menjamin kualitas.
4. Apa yang harus saya berikan untuk mendapatkan penawaran?
Mohon informasikan kepada kami tentang jenis produk yang Anda butuhkan, jumlah pesanan, alamat, dan persyaratan spesifik. Kutipan akan dibuat untuk referensi Anda tepat waktu.
5. Metode pembayaran apa yang Anda sukai? Persyaratan apa yang diterima?
Ketentuan Pengiriman yang Diterima: FOB,CFR,CIF,EXW;
Mata Uang Pembayaran yang Diterima: USD;
Accepted Payment Type: T/T,Western Union; Paypal,BTC
Bahasa yang Digunakan: Bahasa Inggris.
Kategori produk