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Classification of commonly used veterinary drugs: antibacterial drugs, antiviral drugs, antiparasitic drugs, etc.
Classification: Antibiotics are divided into two categories: antibiotics and synthetic antibiotics. The so-called antibiotics are metabolites produced by microorganisms, which can inhibit the growth or kill some other microorganisms. The so-called synthetic antimicrobial drugs are antibacterial substances made by chemical synthesis means, not produced by microbial metabolism. Antibiotics are divided into two classes: antibiotics and synthetic antibiotics.
Antibiotics: Antibiotics are usually divided into eight categories: 1, penicillin: penicillin, ampicillin, amoxicillin, etc.; 2. Cephalosporins (Cephalosporins) : cefalexin, cefhydroxalexin, ceftiofur, Cephalosporin, etc.; 3, aminoglycosides (read the same: generation) : streptomycin, gentamicin, amikacin, neomycin, amprimycin, etc.; 4, macrolides: erythromycin, roxithromycin, tylomycin, etc.; 5, tetracycline: oxytetracycline, doxycycline, aureomycin, tetracycline, etc.; 6. Chloramphenicol: flufenicol, thiamphenicol, etc.; 7. Lincomycin: Lincomycin, clindamycin, etc.; 8, other categories: colistin sulfate, etc.
(a) Penicillins: Source: Penicillins are a class of β-lactam antibiotics with penicillanes as the parent nucleus extracted or further semi-synthesized from penicillium fermentation broth (penicillanes and lactam both refer to a certain chemical structure)
Principle of action: Penicillins interfere with the synthesis of bacterial cell walls, resulting in defects in the new cell walls and lytic bacteria. At a lower concentration, it can only inhibit bacterial growth, and at a higher concentration, it has a powerful bactericidal effect. It has strong antibacterial action against most gram-positive bacteria, some Gram-negative bacteria, various spirochaetes and actinomyces. [Gram refers to a bacterial staining solution, which is divided into gram-positive and Gram-negative bacteria according to the color of the bacteria after staining
At present, antibiotics are usually divided into four categories: the first is the breeding period fungicide: that is, the best effect on bacteria in the large number of bacteria and high-speed reproduction stage, and the role of killing bacteria usually includes penicillins and cephalosporins.
The second category is the quiescent fungicide: that is, the best effect on bacteria in the relatively inactive stage of bacterial reproduction, and it plays the role of killing bacteria. Usually includes aminoglycosides, other classes of colistin and so on.
The third type is rapid bacteriostatic agents: that is, this type of drug can rapidly inhibit the growth and reproduction of bacteria, that is, can slow down the growth and reproduction of bacteria, so that the growth and reproduction cycle of a single bacterium is greatly extended. However, it can not directly kill bacteria, usually including chloramphenicol, macrolides, tetracycline, lincomycin and so on. The fourth class is slow-acting bacteriostatic: that is, this class of drugs can slowly inhibit the growth and reproduction of bacteria. It usually includes sulfonamides and the synergist TMP (trimethoprim).
In general, synergies (i.e. synergies) can be obtained between type I and type II compatibilities. Type 3 and Type 4 compatibility can produce additive effects (i.e., enhanced effects). Antagonistic effects (i.e. reduced effectiveness) may occur between the first and third types of compatibility. Antagonistic effects (i.e. reduced effectiveness) may occur between the first and fourth types of compatibility. The combination of the same class of antibiotics increases the efficacy of some, and reduces the efficacy of some.
In the process of calculating the dosage of veterinary drugs, it is necessary to first understand the weight, capacity, and conversion between international units and milligrams of the drug content, and do not be confused. In addition, the abuse of drugs in the actual livestock and poultry breeding and veterinary clinical has caused a series of problems, so the majority of veterinary workers are required to scientifically and reasonably apply drugs for standardized treatment, so that it can effectively treat diseases, and reduce the cost of breeding, while reducing the problem of drug residues in food.
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