Equilin powder, also known as new generation antipsychotics, refer to antipsychotics whose blocking of dopamine D2 receptor is weaker than that of 5-HT2A receptor, such as clozapine, riparidone, olanzapine, quetiapine, Ziprasidone and other drugs currently used in clinical practice. Among atypical antipsychotics, except for clozapine, which was clinically used earlier (1970s), the others were new antipsychotics that appeared in the late 1990s. Atypical antipsychotics have a significant effect on the treatment of positive and negative symptoms, and are a class of drugs with few extrapyramidal symptoms (EPS) compared with traditional antipsychotics, namely the so-called typical anti-spermatogenic drugs represented by diazepam. These drugs include phenothiazines represented by chlorpromazine and fluphenazine; Butyryl benzenes represented by haloperidol; Thioxanthracene drugs represented by cloprothixene and flupentixene; And the dibenzodiazepines represented by clozapine and Loxapine. Flupentixol, also known as diflupentixol hydrochloride, flucacin, triflupentixol, hydroxypiperazene, is a thioxanthracene atypical antipsychotics, white or light yellow powder at room temperature, bitter taste. Soluble in water, ethanol. Its decanoate is yellow oil, light odor.
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Product Name: | EQUILIN |
Synonyms: | 1,3,5[10],7-ESTRATETRAEN-3-OL-17-ONE;EQUILIN;EQUILINE;1,3,5,7-estratetraen-3-ol-17-one;3-Hydroxyestra-1,3,5(10),7-tetraen-17-one;5(10),7-tetraen-17-one,3-hydroxy-estra-3;Dihydroequilenin;Estra-1,3,5(10),7-tetraen-17-one, 3-hydroxy- |
CAS: | 474-86-2 |
MF: | C18H20O2 |
MW: | 268.35 |
EINECS: | 207-488-6 |
Product Categories: | Intermediates & Fine Chemicals; |
Mol File: | 474-86-2.mol |
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EQUILIN Chemical Properties |
Melting point | 238-240 °C(lit.) |
alpha | D25 +308° (c = 2 in dioxane); D25 +325° (c = 2 in alc) |
Boiling point | 351.51°C (rough estimate) |
density | 1.1096 (rough estimate) |
refractive index | 1.4800 (estimate) |
Fp | 9℃ |
storage temp. | Refrigerator |
solubility | Chloroform (Slightly), Dioxane (Slightly, Heated, Sonicated), DMSO (Slightly, Sonicated) |
form | Solid |
pka | pKa 10.26±0.04(H2O t=23±2) (Uncertain) |
color | White to off-white |
optical activity | +28725 (1% in dioxane) |
Water Solubility | 1.4mg/L(25 ºC) |
Merck | 13,3672 |
BRN | 2624302 |
EPA Substance Registry System | Equilin (474-86-2) |
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