Understanding CAS No. 124-04-9 A Closer Look at Acetylsalicylic Acid

Chemical substances are identified by their unique Chemical Abstracts Service (CAS) numbers, which serve as an essential tool in chemistry and related fields. One such compound is acetylsalicylic acid, known universally by its CAS number 124-04-9. This article delves into the characteristics, uses, and significance of acetylsalicylic acid, which is widely recognized as a key pharmaceutical agent.

Chemical Structure and Properties

Acetylsalicylic acid (ASA) is a derivative of salicylic acid and belongs to a group of compounds known as salicylates. Its chemical formula is C9H8O4, indicating that it comprises nine carbon atoms, eight hydrogen atoms, and four oxygen atoms. The IUPAC name for acetylsalicylic acid is 2-acetoxybenzoic acid, reflecting its molecular structure, which features an acetyl group attached to a salicylic acid backbone.

Acetylsalicylic acid is a white crystalline powder that is relatively soluble in organic solvents, though its solubility in water is limited. Its melting point is around 135 °C, and it has a distinct characteristic of hydrolyzing in the presence of moisture, which can impact its stability in certain formulations. Understanding these properties is crucial for proper handling and storage, particularly in pharmaceutical formulations where precise dosing is necessary.

Acetylsalicylic acid is perhaps best known as a non-steroidal anti-inflammatory drug (NSAID). It primarily functions by inhibiting the enzyme cyclooxygenase (COX), which plays a vital role in the conversion of arachidonic acid into prostaglandins and thromboxanes. Prostaglandins are involved in the mediation of pain, inflammation, and fever, while thromboxanes are crucial for platelet aggregation.

By inhibiting COX enzymes, acetylsalicylic acid effectively reduces the production of these inflammatory mediators, leading to its analgesic (pain-relieving), anti-inflammatory, and antipyretic (fever-reducing) effects. Moreover, its ability to inhibit platelet aggregation gives it unique cardiovascular protective properties, making it a key player in preventing heart attacks and strokes.

Common Uses

The applications of acetylsalicylic acid are diverse, ranging from everyday pain relief to management of chronic conditions. It is commonly used to alleviate mild to moderate pain, including headaches, toothaches, menstrual cramps, and muscle aches. Additionally, due to its anti-inflammatory properties, it is often employed in the treatment of conditions like arthritis.

One of the most significant roles of acetylsalicylic acid in modern medicine is its use in cardiovascular health. Low-dose aspirin therapy is widely recommended for individuals at risk of cardiovascular diseases. Regular intake of low-dose acetylsalicylic acid has been associated with a reduction in the risk of myocardial infarction and stroke, making it a cornerstone in the prevention of cardiovascular events.

Safety and Considerations

While acetylsalicylic acid is generally safe for many users, it is essential to acknowledge potential side effects and contraindications. Common side effects may include gastrointestinal discomfort, bleeding tendencies, and allergic reactions. Individuals with specific health conditions, such as peptic ulcer disease, asthma, or those who are pregnant, should consult a healthcare provider before using ASA.

Moreover, since acetylsalicylic acid can interact with other medications, it is crucial to discuss all current medications with a healthcare professional to avoid adverse interactions. As with all medications, understanding the proper dosages and potential risks is vital for ensuring safe and effective use.

Conclusion

Acetylsalicylic acid, identified by CAS number 124-04-9, stands out as a significant compound in medicine due to its multifaceted benefits. From pain relief to its preventative role in cardiovascular health, ASA has a vital place in pharmaceutical applications. As research continues to unveil more about this compound, its importance in clinical practice will undeniably persist, making it a cornerstone in therapeutic interventions. Proper understanding and responsible usage of acetylsalicylic acid can lead to improved health outcomes for countless individuals worldwide.