Palmitoylethanolamide PEA is an endogenous fattyacid amide, belonging to the class of nuclear factor agonists. PEA is one of themost important endogenous painkilling and anti-inflammatory compounds and has been shown to effective for both acute and chronic pain. Because the substanceacts as a natural painkiller, it is an excellent alternative for conventional medications that might cause side effects.
Palmitoylethanolamide is a natural substance produced by the body and it is very effective and safe to use as a supplement for pain and reduce inflammation.
PEA can be synthesized within the human body from the abundant fatty acid palmitic acid, but it is not dependent or influenced by dietary consumption of fatty acids. Palmitic acid in the diet is derived from dairy products such as cheese and butter, palm tree oil, and animal meat products. However, increasing palmitic acid in the hope of increasing endogenous PEA synthesis will not be effective.
The anti-inflammatory properties of PEA are due to its ability to inhibit inflammation-causing proteins called cytokines. Cytokines are released during periods of inflammation. PEA can suppress the secretion of tumor necrosis factor alpha (TNF alpha), a cytokine, while also inhibiting the release of interleukins. Interleukins are a specific class of cytokines which belong in the immunological system and are activated during the process of inflammation.
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Article | Especificació | Resultat |
Aparença | Fine white to off-white crystal powder | Conforma |
Color | White to Off-white | Conforma |
Identificació | Positive | Conforma |
Pèrdua en l'assecat | ≤ 1.0% | 0.28% |
Water | ≤ 1.0% | 0.17% |
Residue on ignition | ≤ 0.10% | 0.04% |
Purity (HPLC) | ≥ 99.0% | 99.54% |
Heavy metal | ||
(Pb),mg/kg | ≤ 0.5 | Conforma |
(As), mg/kg |
≤ 0.15 | Conforma |
(Cd),mg/kg | ≤ 2.5 | Conforma |
(Hg), mg/kg |
≤ 1.5 | Conforma |
Solvent residue |
||
Ethanol | ≤ 0.5% | Not detected |
Microbiological control | ||
Recompte total de plaques | ≤ 10,000cfu/g | Conforma |
Yeast & Mold | ≤ 300cfu/g | Conforma |
Coliforms | ≤ 10cfu/g | Conforma |
E.Coli | Negative/10g | Conforma |
Salmonella sp. | Negative/25g | Conforma |
Staph Aureus | Negative/10g | Conforma |
Pseudomonas aeruginosa |
Negative/25g | Conforma |
Conclusió | The results conform to enterprise Standard |
Palmitoylethanolamide(pea) Powder is an endogenous fatty acid amide, belonging to the class of nuclear factor agonists.
PEA has been demonstrated to bind to a receptor in the cell-nucleus (a nuclear receptor) and exerts a great variety of biological functions related to chronic pain and inflammation. The main target is thought to be the peroxisome proliferator-activated receptor alpha (PPAR-α).It is an endogenous fattyacid amide, belonging to the class of nuclear factor agonists. PEA is one of themost important endogenous painkilling and anti-inflammatory compounds and has been shown to effective for both acute and chronic pain. Because the substanceacts as a natural painkiller, it is an excellent alternative for conventionalmedications that might cause side effects.
1. Anti-inflammatory:PEA is believed to possess anti-inflammatory properties, helping to alleviate inflammation and pain.
2. Analgesic:PEA can relieve various types of pain, including neuropathic pain and chronic pain syndromes.
3. Neuroprotection:PEA may contribute to protecting the nervous system and could be beneficial for certain neurological conditions.
4. Immune modulation:PEA may have some immune-modulating effects, assisting in regulating immune system function.
5. Skincare:Some studies suggest that PEA may be beneficial for the skin and can be used to treat and maintain certain skin conditions.
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