3-aminophenone, also known as 3-phenylpyruvate, is an organic compound. Nature:
- Appearance: 3-aminophenone is colorless or slightly yellow crystal.
- Solubility: It is insoluble in water and soluble in organic solvents such as alcohols and ethers.
- Chemical properties: 3-aminophenone is an aromatic compound that can undergo nucleophilic substitution and alkylation in some chemical reactions.
-3-aminoacetophenone is a common intermediate in organic synthesis and can be used to synthesize many important organic compounds.
-3-aminoacetophenone can also be used as an intermediate in the synthesis of dye pigments.
M-aminoacetophenone is an important pharmaceutical and organic intermediate, and its downstream products have important uses. For example, m-hydroxyacetophenone is an intermediate for the synthesis of epinephrine drugs, m-chlorophenone can be used for the synthesis of new special drugs such as bronchiectasis and anti-purpura drugs, and 3-acetamidoacetophenone is an intermediate for the synthesis of sedative hypnotic indiplon.
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Molecular Formula | C8H9NO |
Molar Mass | 135.16 |
Density | 1.1031 (rough estimate) |
Melting Point | 94-98°C(lit.) |
Boling Point | 289-290°C(lit.) |
Flash Point | 289-291°C |
Water Solubility | 7.056g/L(37.5 ºC) |
Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 1.319Pa at 25℃ |
Appearance | Brown crystal |
Color | Yellow to light brown crystalline powder |
Merck | 14,413 |
BRN | 386009 |
pKa | 3.41±0.10(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.5700 (estimate) |
MDL | MFCD00007796 |
Physical and Chemical Properties | Melting point 95-98°C boiling point 289-290°C |
Use | For the synthesis of phenylephrine drugs, hypnotics such as zaleplon, and can be used as raw materials for organic synthesis |
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