2-hydroxypyrimidine (2-amino-4,6-dihydroxypyrimidine) is also known as DHP (Dihydroxypyrimidine).
Properties: 2-amino-4, 6-dihydroxypyrimidine is a white crystalline powder that is soluble in water and some organic solvents. It is a weak alkaline compound with two amino (-NH2) and two hydroxyl (-OH) functional groups.
Preparation method: The common method for preparing 2-amino-4, 6-dihydroxypyrimidine is to react ethyl acetoacetate with urea. Acetyl - 2-amino-4, 6-dihydroxypyrimidine is produced by heating ethyl p-acetoacetate with urea under alkaline conditions. Then, by hydrolysis under acidic conditions, 2-amino-4, 6-dihydroxypyrimidine is obtained.
Safety information: 2-amino-4, 6-dihydroxypyrimidine is not currently classified as toxic or hazardous. As with any chemical, safety precautions should still be taken when using it. Avoid direct contact with skin and eyes, and wear personal protective equipment when using. Avoid contact with oxidants and hygroscopic substances during use and storage. In any case, it should be safely operated and properly handled according to the actual situation.
Important pharmaceutical intermediates.
Used as an intermediate of herbicides benzsulfuron and pyrisulfuron.
2-amino-4, 6-dihydroxypyrimidine is an intermediate in the preparation of 2-amino-4, 6-dimethoxy-pyrimidine, which can be used in the production of sulfonylurea herbicides, such as benzsulfuron, pyrisulfuron, nicosulfuron, etc.
Used for the synthesis of ADCP, ACMP and ADMP.
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Product Name: | 2-Amino-4,6-dihydroxypyrimidine |
Synonyms: | 2-amino-6-hydroxy-4(1h)-pyrimidinon;2-amino-6-hydroxy-4(1H)-Pyrimidinone;2-AMino-4,6-dioxypyriMidine;2-AMino-6-hydroxy-4(3H)-pyriMidinone;NSC 15920;NSC 18692;2-aMino-6-hydroxypyriMidin-4(3H)-one;2-AMino-4,6-dihydroxypyriMidine, 97+% |
CAS: | 56-09-7 |
MF: | C4H5N3O2 |
MW: | 127.1 |
EINECS: | 200-256-5 |
Product Categories: | Amines;Aromatics;5-FOA; |
Mol File: | 56-09-7.mol |
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2-Amino-4,6-dihydroxypyrimidine Chemical Properties |
Melting point | >300 °C (lit.) |
Boiling point | 235.85°C (rough estimate) |
density | 1.4748 (rough estimate) |
refractive index | 1.5000 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | Soluble in Aqueous Alkali. |
pka | 7.45±0.10(Predicted) |
form | Powder |
color | Off-white to light pink or light yellow |
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