Clindamycin Phosphate

Pharmaceutical Intermediate CAS 24729-96-2 99% Powder Clindamycin Phosphate

產品名稱：
Clindamycin Phosphate
年級：
醫藥級
特性：
白色粉末
包裝：
25公斤/桶
最小起訂量：
1 kilo
貯存：陰涼乾燥處
保存期限：2年

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產品描述

Clindamycin Phosphate is used primarily to treat infections caused by susceptible anaerobic bacteria, including infections of the respiratory tract,skin and soft tissue infections, and peritonitis.In patients with hypersensitivity to penicillins,Clindamycin Phosphate may be used to treat infections caused by susceptible aerobic bacteria as well.

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應用

Clindamycin Phosphate is a semi synthetic derivatives of clindamycin,has no antibacterial activity in vitro enter the body quickly hydrolyzed to clindamycin and to show its pharmacological activity,the antibacterial spectrum of antibacterial activity,and the therapeutic effect of clindamycin and the same,but its lipid solubility and permeability of Pickering mycin,oral or intramuscular injection and intravenous drip.

Clindamycin is used primarily to treat infections caused by susceptible anaerobic bacteria, including infections of the respiratory tract, skin and soft tissue infections, and peritonitis.In patients with hypersensitivity to penicillins, clindamycin may be used to treat infections caused by susceptible aerobic bacteria as well. It is also used to treat bone and joint infections, particularly those caused by Staphylococcus aureus. Topical application of clindamycin phosphate can be used to treat mild to moderate acne.

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規格

Items	標準	結果
特徵	A white or almost white ,slightly hygroscopic powder	A white ,slightly hygroscopic powder
Solubility	This product is easily soluble in water, slightly soluble in methanol, almost insoluble in ethanol, acetone	conform
鑑別	A:the infrared light absorption spectrum of this product should be consistent with that of the reference product B:the retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assay	符合 conform
Crystallinity	Meets the requirements	conform
PH	PH 3.5-4.5	3.8
Water by KF	≤6.0%	0.62%
Organic impurities
Lincomycin phosphate	≤1.0%	0.26%
Lincomycin	≤0.5%	None detected
Clindamycin B phosphate	≤1.5%	0.21%
7-epiclindamycin phosphate	≤0.8%	0.11%
Clindamycin 3-phosphate	≤0.3%	0.064%
Clindamycin	≤0.5%	0.16%
Any individuai unspecified impurity:	≤1.0%	0.33%
Total impurities	≤4.0%	1.2%
Bacterial endotoxins test	<0.58EU/mg	<0.1EU/mg
Residual solvents	Acetone≤0.5% ethanol≤0.5% methanol≤0.3% pyridine≤0.02% chlorofor≤0.006%	None detected 0.002% None detected None detected None detected
測定	Not less than 758ug/mg on the anhydrous basis	838ug/mg
CONCLUSION	This product conforms with usp43