Sodium triacetyloxyborohydride is an organic boron compound with the chemical formula C6H10BNaO6.
Nature:
1. Appearance: Sodium triacetyloxyborohydride is usually a colorless crystalline solid.
2. Stability: It is relatively stable at room temperature and soluble in many organic solvents.
3. Toxicity: Compared with other boron compounds, sodium triacetyloxyborohydride has lower toxicity.
Preparation method:
The preparation method of sodium triacetoxyborohydride is generally obtained by the reaction of aluminum triacetoxyborohydride with sodium hydroxide. The specific process can be referred to relevant literature such as the Organic Chemical Synthesis Manual.
Security information:
Sodium triacetyloxyborohydride is irritating to the skin and eyes. During operation, be careful to avoid contact. If necessary, wear protective gloves and goggles.
2. During storage and handling, avoid contact with water vapor in the air as it is sensitive to water and may decompose.
Purpose 1
The new type of catalyst for reduced-amination has excellent universality and selectivity. The reaction conditions are mild, the catalytic reduction performance is good, and it is easy to separate and purify. Both the catalyst itself and the by-products are non-toxic and cause no pollution to the environment, making it the preferred catalyst for reduced-amination reactions.
Use 2
Reagents, used for the reductive amination of ketones and aldehydes, the reductive amination/lactam of carbonyl complexes and amines, as well as the reductive amination of aryl aldehydes.
Purpose:
1. Reducing agent: Sodium triacetyloxyborohydride is a commonly used reducing agent in organic synthesis, which can effectively reduce aldehydes, ketones and other compounds to the corresponding alcohols.
2. Catalyst: Sodium triacetyloxyborohydride can be used as a catalyst in some organic synthesis reactions, such as the Bal-Fischer ester synthesis and the Swiss-Hausmann reaction, etc.
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Molecular Formula | C6H10BNaO6 |
Molar Mass | 211.94 |
Density | 1.36[at 20℃] |
Melting Point | 116-120 °C (dec.) (lit.) |
Boling Point | 111.1℃[at 101 325 Pa] |
Water Solubility | reacts |
Solubility | Soluble in dimethyl sulfoxide, methanol, benzene, toluene, terahydrofuran, dioxane and methylene chloride. |
Vapor Presure | 0Pa at 25℃ |
Appearance | Powder |
Color | White |
Merck | 14,8695 |
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