Aug . 14, 2025 03:00 Back to list
In the intricate world of fine chemicals and pharmaceutical intermediates, the purity and reliability of core building blocks are paramount. 4-Chromanone CAS 491-37-2 stands out as a critical compound, widely recognized for its versatile chemical structure and reactivity. This cyclic ketone, also known as 2,3-Dihydro-4H-1-benzopyran-4-one, serves as an essential precursor in the synthesis of a diverse array of biologically active molecules, including pharmaceuticals, agrochemicals, and specialized polymers. Its unique chromanone scaffold provides a stable yet reactive platform for various organic transformations, making it indispensable for chemists pushing the boundaries of discovery and development across multiple high-tech industries. Understanding its properties, advanced manufacturing, and strategic applications is key for stakeholders seeking to optimize their chemical processes and product portfolios.
The demand for high-purity 4-Chromanone CAS 491-37-2 is steadily rising, driven by significant advancements in targeted drug delivery systems and the continuous innovation within material science. This upward trend is particularly evident in the pharmaceutical sector, where the compound is utilized in the synthesis of anti-inflammatory agents, anticancer drugs, and neuroprotective compounds. Furthermore, its role extends to the agrochemical industry for developing novel pesticides and herbicides with enhanced efficacy and reduced environmental impact. The global fine chemical market’s expansion, coupled with stringent quality requirements, necessitates reliable sourcing of such pivotal intermediates. Manufacturers and researchers alike prioritize suppliers who can guarantee not only exceptional purity and consistent quality but also robust technical support and scalable production capabilities to meet evolving market demands.
The performance and applicability of 4-Chromanone CAS 491-37-2 in industrial and research settings are directly dependent on its precise technical specifications. Our commitment to quality ensures that every batch meets rigorous standards, providing consistent results for your synthesis needs. Below is a comprehensive table detailing the critical parameters that define this high-quality chemical intermediate, demonstrating its suitability for demanding applications across various sectors. These specifications are routinely verified through advanced analytical techniques, guaranteeing the integrity and purity of the product.
Parameter | Value/Specification |
---|---|
CAS Number | 491-37-2 |
Molecular Formula | C9H8O2 |
Molecular Weight | 148.16 g/mol |
Appearance | White to off-white crystalline powder |
Purity (HPLC) | ≥ 98.0% (typically 99.0%+) |
Melting Point | 50-55 °C |
Boiling Point | 248-250 °C at 760 mmHg |
Loss on Drying | ≤ 0.5% |
Residue on Ignition | ≤ 0.1% |
Storage Condition | Store in a cool, dry, dark place under inert gas. |
The production of high-grade 4-Chromanone CAS 491-37-2 involves a meticulously controlled multi-step organic synthesis process, ensuring superior purity and consistent yield. Our manufacturing process begins with selecting premium-grade raw materials, typically involving a proprietary precursor. The initial step often involves a cyclization reaction, where the precursor undergoes ring closure under specific catalytic conditions to form the chromanone scaffold. This critical stage is carefully monitored for temperature, pressure, and reaction time to maximize yield and minimize impurities. Subsequent steps involve targeted oxidation, followed by rigorous purification through techniques such as fractional distillation, recrystallization, or column chromatography, depending on the desired purity level and scale. Each stage benefits from advanced process control systems, ensuring optimal reaction kinetics and product quality.
Quality assurance is integrated into every phase of the manufacturing process for 4-Chromanone CAS 491-37-2. We adhere to stringent international standards, including ISO 9001:2015, ensuring consistent quality management. Post-synthesis, each batch undergoes comprehensive analytical testing using state-of-the-art instruments. Techniques like High-Performance Liquid Chromatography (HPLC) are used to determine purity, Gas Chromatography-Mass Spectrometry (GC-MS) for impurity profiling, Nuclear Magnetic Resonance (NMR) spectroscopy for structural confirmation, and Karl Fischer titration for moisture content. This rigorous testing regimen guarantees that the product meets or exceeds industry standards for purity (typically >98%), stability, and long-term performance, making it suitable for demanding applications in pharmaceutical synthesis, where regulatory compliance is critical.
The unique chemical structure of 4-Chromanone CAS 491-37-2 makes it a highly valuable intermediate across a spectrum of advanced industries. In the pharmaceutical sector, it serves as a crucial building block for synthesizing various therapeutic agents. For instance, its derivatives are explored for their anti-inflammatory, antioxidant, and antimicrobial properties. It is also instrumental in the development of certain anticancer drugs and compounds targeting neurological disorders. Its ability to readily undergo functionalization and ring-expansion reactions allows for the creation of complex molecular architectures required for novel drug discovery programs. This versatility significantly reduces synthesis steps for pharmaceutical companies, leading to more efficient and cost-effective production of active pharmaceutical ingredients (APIs).
Beyond pharmaceuticals, 4-Chromanone CAS 491-37-2 finds significant utility in the agrochemical industry, contributing to the synthesis of new generation pesticides, herbicides, and fungicides that are both potent and environmentally conscious. Its derivatives can offer improved selectivity and reduced persistence in the environment. In the realm of material science, this compound acts as a monomer or cross-linking agent for specialized polymers, enabling the creation of advanced materials with enhanced thermal stability and optical properties. For example, it can contribute to the development of UV-resistant coatings or functionalized resins. Furthermore, its application extends to academic research and custom synthesis, where its unique reactivity profile is continually explored for novel chemical transformations and the development of new synthetic methodologies.
Choosing a specialized supplier for 4-Chromanone CAS 491-37-2 offers distinct technical advantages that directly impact your project's success. Our expertise in fine chemical synthesis ensures not only superior product purity but also consistency across batches, critical for reliable experimental results and scalable industrial production. We leverage advanced synthetic methodologies and purification techniques to minimize impurities and maximize yield, often exceeding standard industry benchmarks. This translates into less rework for our clients, reduced consumption of downstream purification reagents, and ultimately, a more efficient and cost-effective overall process. Our technical team possesses deep knowledge of 4-Chromanone CAS 491-37-2 chemistry, allowing us to offer unparalleled technical support and troubleshooting assistance for complex applications.
Our commitment to quality is underscored by robust quality control (QC) protocols that align with cGMP principles where applicable, and our adherence to ISO standards provides an authoritative benchmark for our operational excellence. We provide comprehensive Certificates of Analysis (CoA) with every shipment, detailing purity, spectroscopic data, and other critical parameters, fostering complete transparency and trustworthiness. Furthermore, our substantial R&D investment enables continuous improvement in synthesis efficiency and purity profiles, potentially offering a longer effective shelf life for the intermediate and reducing long-term material degradation concerns for our customers. This dedication to technical superiority ensures that our 4-Chromanone CAS 491-37-2 not only meets but often surpasses the demanding requirements of pharmaceutical, agrochemical, and advanced material industries, providing a competitive edge for our partners.
Recognizing that every client's project has unique requirements, we offer extensive customization and tailored solutions for 4-Chromanone CAS 491-37-2. Whether you require specific purity levels beyond standard specifications, specialized packaging to protect against environmental factors, or a particular batch size ranging from laboratory scale to metric ton quantities, our flexible manufacturing capabilities are designed to accommodate. Our technical team works closely with your R&D and procurement departments to understand the precise application and necessary parameters, ensuring the supplied material integrates seamlessly into your existing processes. This bespoke approach minimizes the need for internal re-purification or extensive compatibility testing, accelerating your project timelines and reducing associated costs.
Our expertise extends to offering custom synthesis services for 4-Chromanone CAS 491-37-2 derivatives or related chromanone compounds that may not be commercially available off-the-shelf. Leveraging our state-of-the-art facilities and experienced chemists, we can undertake complex multi-step syntheses under confidentiality agreements, providing a reliable and efficient pathway for novel chemical entities. This commitment to collaborative problem-solving and our agile production planning solidify our position as a preferred partner for companies seeking not just a supplier, but a strategic collaborator in chemical innovation. We are dedicated to building long-term relationships based on trust, consistent quality, and responsive service.
A1: Our standard 4-Chromanone CAS 491-37-2 typically has a purity of ≥ 98.0% as determined by HPLC, with many batches exceeding 99.0%. We can also offer higher purity grades upon request for specialized applications.
A2: 4-Chromanone CAS 491-37-2 is primarily used as a versatile building block in the synthesis of pharmaceuticals (e.g., anti-inflammatory, anticancer drugs), agrochemicals (pesticides, herbicides), and advanced materials. It's also utilized in academic research for novel organic synthesis.
A3: We adhere to stringent ISO 9001:2015 certified quality management systems. Each batch of 4-Chromanone CAS 491-37-2 undergoes comprehensive testing including HPLC for purity, GC-MS for impurity profiling, NMR for structural confirmation, and Karl Fischer for moisture content. A Certificate of Analysis (CoA) is provided with every shipment.
A4: Lead times for 4-Chromanone CAS 491-37-2 vary based on order size and current stock levels. For standard quantities, we aim for a delivery cycle of 1-2 weeks. For larger, custom orders, our sales team will provide a detailed timeline based on production schedules. We are committed to timely delivery and clear communication throughout the process.
A5: Absolutely. Our dedicated team of experienced chemists and technical specialists is available to provide comprehensive technical support. This includes guidance on optimal usage, handling precautions, and assistance with any synthesis-related queries you might encounter while working with 4-Chromanone CAS 491-37-2. Your success is our priority.
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