Metoclopramide Hydrochloride

Metoclopramide Hydrochloride is an antiemetics that can be used in chemotherapy, radiotherapy, surgery, craniocerebral injury, sequelae of brain trauma, naval operations, and drug-induced vomiting. It can also be used for the symptomatic treatment of nausea and vomiting symptoms of acute gastroenteritis, biliary tract pancreas, urosis and other diseases. It can also be used before diagnostic duodenal intubation to facilitate smooth intubation. Gastrointestinal barium X-ray examination can alleviate nausea and vomiting reaction; Promote the passage of barium.

Metoclopramide Hydrochloride is a dopamine-2 (D2) receptor antagonist, and has a receptor excitatory effect of 5-tibiotryptamine 4 (5-HT4), and has a mild inhibitory effect on 5-HT3 receptors. It can act on the dopamine receptor in the emetic chemoceptive area (CTZ) of the medulla oblong and raise the threshold of CTZ, which has a powerful central antiemetic effect. Metoclopramide Hydrochloride can also block hypothalamic dopamine receptors, inhibit prolactin inhibitory factor, and promote the secretion of prolactin, so it has certain prolactin effect. The inhibitory effect on other parts of the center is relatively small, has a weak stabilizing effect, and less causes hypnotic effect. The effect on gastrointestinal tract is mainly in the upper digestive tract, promoting the movement of stomach and upper intestinal segment; Increase the tension of the resting gastrointestinal muscle, increase the tension and contraction amplitude of the lower esophageal muscle, and increase the lower end of the esophageal pressure. Block gastroesophageal reflux, strengthen stomach and esophageal peristalsis, enhance the clearance ability of esophageal contents, promote gastric empting, promote the relaxation of pylorus, duodenum and upper jejunum, and form the functional coordination between the stomach body and upper gut. These effects can also enhance the antinausea effect of this product. The effect of this product on small intestine and colon delivery is uncertain.

We have many high-quality factories with deep cooperation, which can provide you with high quality products and competitive prices. And we can also give discounts for bulk purchases.And we cooperate with many professional freight forwarding companies, can deliver products safely and smoothly to your hands. Delivery time is about 3-20 days after confirmation of payment.

1. Are you a factory or a trading company?
We are a compnay integrating industry and trade,providing one-stop service.OEM could be accepted.

2. Do you provide samples? Is it free or extra?
Free samples.The sample's freight fee need to be paid by your side.

3. Do you have any certificates related to quality control?
ISO 9001:2008 certification to ensure quality.

4. What should I provide to get a quotation?
Pls inform us of the product type which you need,order quantity,address and specific requirements.The quotation will be made for your reference in time.

5. What kind of payment method do you prefer? What kind of terms are accepted?
Accepted Delivery Terms: FOB,CFR,CIF,EXW;
Accepted Payment Currency:USD;
Accepted Payment Type: T/T,Western Union; Paypal,Trade Assurance.
Language Spoken:English.