Enrofloxacin is also known as ethyl ciprofloxacin, Enfloxacin. Is a slightly yellow or light yellow crystalline powder, bitter taste, insoluble in water, this product has been designated by the state as a special drug for animals.
Enrofloxacin belongs to the chemical synthesis of fluquinolone bacteriostatic, soluble in sodium hydroxide solution, methanol, cyanomethane and other organic solvents.
This product is a broad spectrum bactericidal drug, has specific effects on mycoplasma. It has bactericidal effect on Escherichia coli, Klebsiella, Salmonella, Proteus, Pseudomonas aeruginosa, Haemophilus, Pasteurella multocida, Pasteurella hemolyticus, Staphylococcus aureus, streptococcus and so on.
Enrofloxacin can be used as an animal drug, has a long half-life in animals, has good tissue distribution, is a broad-acting bacteriostatic agent, has antibacterial effect on gram-positive bacteria, negative bacteria and mycoplasma, has been used in cultured fish vibriosis and Escherichia coli disease control.
This product is a synthetic third generation quinolone antibacterial drug, also known as ethyl ciprofloxacin, for livestock and aquatic special quinolone antibacterial drugs. It can bind to the bacterial DNA cyclotase subunit A, thus inhibiting the cutting and linking function of the enzyme, preventing the replication of bacterial DNA, and showing antibacterial effect. With broad-spectrum antibacterial activity and strong permeability, this product has a strong killing effect on gram-negative bacteria and a good antibacterial effect on Gram-positive bacteria, good oral absorption, high and stable blood concentration, can be widely distributed in tissues, its metabolic product is ciprofloxacin, and still has a strong antibacterial effect. It has strong antibacterial activity against almost all pathogens in aquatic animals. It is effective against serious infections caused by drug-resistant pathogens and has no cross-resistance with other antimicrobials.
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The absorption of internal administration and intramuscular injection is rapid and complete, and the blood drug level reaches its peak in 0.5-2 hours. In addition to the central nervous system, almost all tissues have a higher concentration of drugs than plasma, which is conducive to the treatment of systemic infections and deep tissue infections. This product is eliminated by renal and non-renal means, and about 15%-50% of the drug form is excreted through urine. In animals, it is metabolized mainly by deethylating to ciprofloxacin.
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