1,2,4, 5-phenyltetramine tetrachloride is a compound,
Nature:
1,2,4, 5-phenyltetramine tetrachloride hydrochloride is a colorless crystalline solid that can be dissolved in water and some organic solvents. It is strongly acidic and soluble in alkaline solutions.
Preparation:
A common method for preparing 1,2,4, 5-phenyltetramine tetrachloride hydrochloride is to dissolve aniline in hydrochloric acid and then react with nitrous acid to obtain nitrosianiline hydrochloride through nitrosylation. Subsequently, 1,2,4, 5-phenyltetramine tetramine hydrochloride was obtained by coupling reaction with aniline.
Safety information:
1,2,4, 5-phenyltetramine tetramine hydrochloride can be irritating and corrosive and should be avoided in contact with skin and eyes. When using, you should take appropriate personal protective equipment, such as wearing goggles, gloves and protective clothing.
1,2,4, 5-phenyltetramine tetrahydrochloride light purple powder, used for synthetic material intermediates and pharmaceutical research and development intermediates, can be used in laboratory research and development and chemical medicine synthesis process.
1,2,4, 5-phenyltetramine tetrahydrochloride directly blocks the phosphorylation of focal adhesion kinase (FAK) in a dose-and time-dependent manner, and also shows breast tumor regression in vivo. Targeting the Y397 site of FAK with FAK inhibitor 14 has been proposed to be effective for cancer therapy.
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Molecular Formula | C6H11ClN4 |
Molar Mass | 174.63 |
Density | 1.401g/cm3 |
Melting Point | ≥300°C(lit.) |
Boling Point | 400.9°C at 760 mmHg |
Flash Point | 233.6°C |
Solubility | H2O: soluble20mg/mL, clear |
Vapor Presure | 1.23E-06mmHg at 25°C |
Appearance | powder |
Color | white |
BRN | 3701344 |
Storage Condition | room temp |
Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month. |
Refractive Index | 1.827 |
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